Microbial infections of the cornea can have serious consequences, including blindness in the worst case. The treatment of keratitis, a condition caused by certain pathogens, always presents major challenges to ophthalmologists. These corneal infections frequently cannot be successfully treated with the therapies currently available. Researchers are pursuing a new approach: contact lenses with germicidal properties could offer an alternative to conventional therapies. Initial tests in the laboratory and on donor corneas were successful.