New genes associated with the leading cause of blindness
A new study identifies genes associated with Age-related Macular Degeneration (AMD) that could represent new targets for future drug development.
Faulty molecular master switch may contribute to AMD
A signaling pathway controlled by transforming growth factor beta (TGF-beta) could be involved in the progression of age-related macular degeneration (AMD).
Genetic study provides novel insights into the evolution of skin color
Skin color is one of the most visible and variable traits among humans and scientists have always been curious about how this variation evolved. Now, a study of diverse Latin American populations has identified new genetic variations associated with skin color.
Cultivating 4D tissues: The self-curving cornea
Scientists have developed a biological system which lets cells form a desired shape by molding their surrounding material -- in the first instance creating a self-curving cornea. The astonishing video shows the cornea molding itself into a bowl-like structure over the course of 5 days.
New findings on eye-signal blending
Knowing precisely where the signals meet and the brain processes them is vital to treating amblyopia, or reduced vision in one eye because the brain and eye aren't working together properly.
Treating a chalazion at home
A chalazion is a small, painless lump that can develop on the eyelid. Anyone can a get a chalazion, but they are more common in people with an underlying skin condition. Chalazia usually heal on their own within a few weeks. Learn more here.
Researchers rescue photoreceptors, prevent blindness in animal models of age-related macular degeneration
Using a novel patient-specific stem cell-based therapy, researchers prevented blindness in animal models of geographic atrophy, the advanced 'dry' form of age-related macular degeneration (AMD), which is a leading cause of vision loss among people age 65 and older. The protocols established by the animal study set the stage for a first-in-human clinical trial testing the therapy in people with geographic atrophy, for which there is currently no treatment.
Pioneering surgery restores movement to children paralyzed by acute flaccid myelitis
An innovative and complex surgery involving nerve transfers is restoring movement to young patients with paralysis caused by acute flaccid myelitis.
A human model to test implants for cataract surgery
New research uses an improved laboratory model to simulate cataract surgery on human donor eyes.
Computers can be a real pain in the neck
Many people slouch or strain their necks while working at the computer. A new study shows how jutting the head forward to read more closely compresses the neck and leads to neck and shoulder problems.
'Christmas berry' plant compound could fight Uveal melanoma
A molecule derived from a type of primrose could prove to be a potent inhibitor of metastatic growth for a rare and aggressive cancer.
'Bionic face' experiments could lead to new treatment approach for facial paralysis
An implantable neuroprosthetic device may one day provide a new approach to restoring more natural facial movement in patients with one-sided facial paralysis (hemifacial palsy), suggests a new study.
300 blind mice uncover genetic causes of eye disease
Hundreds of new genes linked to blindness and other vision disorders have been identified in a screen of mouse strains. Many of these genes are likely important in human vision and the results could help identify new causes of hereditary blindness in patients.
Sight-saving treatment for eye infection or trauma
Scientists have developed a novel eye drop that rapidly reduces sight-threatening scarring to the surface of the eye.
Molecule discovery holds promise for gene therapies for psoriasis
Scientists have discovered a protein that could hold the key to novel gene therapies for skin problems including psoriasis - a common, chronic skin disease that affects over 100 million people worldwide.
How the brain reacts to loss of vision
If mice lose their vision immediately after birth due to a genetic defect, this has a considerable impact, both on the organization of the cerebral cortex and on memory. Researchers demonstrated that, in the months after blindness emerged, the density of neurotransmitter receptors that regulate excitation balance and are required for memory encoding was altered in all areas of the cortex that process sensory information. Furthermore, the hippocampus, a brain region that plays a crucial role in memory processes, was profoundly affected.
Eye-opening study differentiates iPS cells into various ocular lineages
Researchers revealed that culturing human induced pluripotent stem cells with different isoforms of the extracellular component laminin led to the creation of cells specific to different parts of the eye, including retinal, corneal, and neural crest cells. They showed that the different laminin variants affected the cells' motility, density, and interactions, resulting in their differentiation into specific ocular cell lineages. Cells cultured in this way could be used to treat various ocular diseases.
A compound being developed to treat eye disease also kills leukemia cells
An active ingredient in eye drops that were being developed for the treatment of a form of eye disease has shown promise for treating an aggressive form of blood cancer. Scientists have found that this compound, which targets an essential cancer gene, could kill leukemia cells without harming non-leukemic blood cells. The results reveal a potential new treatment approach for an aggressive blood cancer with a poor prognosis.
CBD in marijuana may worsen glaucoma, raise eye pressure
A study has found that CBD -- a major chemical component in marijuana -- appears to increase pressure inside the eye of mice, suggesting the use of the substance in the treatment of glaucoma may actually worsen the condition.
Injection improves vision in a form of childhood blindness
A new treatment for patients with a form of congenital retinal blindness has shown success in improving vision, according to new results.
Do I have night blindness?
Night blindness occurs when an existing eye condition leads to an inability to see clearly in dim light. Treatments depend on the cause but often involve managing the underlying condition. Learn more here.
Mass spectrometry sheds new light on thallium poisoning cold case
In 1994, Chinese university student Zhu Ling began experiencing stomach pain, hair loss and partial paralysis. By the time doctors diagnosed Ling with thallium poisoning about four months later, she was in a coma. Two decades after the poisoning, mass spectrometry has been used to analyze several of Ling's hairs collected in 1994 and 1995 and established a timeline of her poisoning.
Resting easy: Oxygen promotes deep, restorative sleep
Exposure to high levels of oxygen encourages the brain to remain in deep, restorative sleep, according to a new study.
Unlocking the secrets of how cells communicate offers insights into treating diseases
Researchers have made a significant breakthrough by developing the 3D structure of proteins from inside the eye lens that control how cells communicate with each other, which could open the door to treating diseases such as cataracts, stroke and cancer.
Are you stressed? Your eyes may provide a window into your mental workload
With nearly breakneck speed, the demands of work productivity in today's society seem to have increased tenfold. Enter multitasking as a way to cope with the insistence that tasks be completed almost immediately. Previous studies on workload and productivity include physical aspects, such as how much a person walks or carries, but they do not take into account a person's state of mind. Now, researchers have discovered a person's eyes may offer a solution.
The naked eye alone is not enough to ensure the accurate diagnosis of skin cancer, say experts
The visual inspection of a suspicious skin lesion using the naked eye alone is not enough to ensure the accurate diagnosis of skin cancer, a group of experts have concluded.
Whole-brain imaging of mice during behavior
In a new study, researchers demonstrate how functional ultrasound imaging can yield high-resolution, brain-wide activity maps of mice for specific behaviors. The non-invasive technology has promising applications for ophthalmologic, neurologic and psychiatric diseases.
Immune checkpoints could be key to treating autoimmune disease myasthenia gravis
The PD-1 immune checkpoint is essential for self-recognition by the immune system, with disruption of the pathway associated with several autoimmune disorders. However, the involvement of PD-1 and its ligand PD-L1 in muscle-weakening autoimmune disease myasthenia gravis is unclear. Now, researchers have linked increased PD-L1 expression in the muscles of myasthenia gravis patients with disease severity and shown that this could ultimately help control the immune response and modulate disease symptoms.
Screen time disrupts sleep by resetting internal clocks
Prolonged exposure to light late at night causes certain cells in the eye to reset the body's internal clock and upset its rhythms, which can harm health.
How to make saline solution
Saline solution is easy to make at home using salt and water. Here, we look at how to make saline solution, its uses, and how to store the solution safely.
Single cell sequencing sheds light on why cancers form in specific cell types
Researchers build, then use single cell sequencer to identify and characterize a subpopulation of cells in the eye where cancer originates.
How changing labs revealed a chemical reaction key to cataract formation
Researchers working to understand the biochemistry of cataracts have made a surprising finding: A protein that was long believed to be inert actually has an important chemical function that protects the lens of the eye from cataract formation.
Why screen time can disrupt sleep
For most, the time spent staring at screens -- on computers, phones, iPads -- constitutes many hours and can often disrupt sleep. Now, researchers have pinpointed how certain cells in the eye process ambient light and reset our internal clocks, the daily cycles of physiological processes known as the circadian rhythm. When these cells are exposed to artificial light late into the night, our internal clocks can get confused, resulting in a host of health issues.
How a small molecule promotes removal of excess cholesterol
Scientists have determined the structure of the activated form of an enzyme that helps to return excess cholesterol to the liver.
Electrical stimulation in the nose induces sense of smell in human subjects
Physicians have, for the first time, induced a sense of smell in humans by using electrodes in the nose to stimulate nerves in the olfactory bulb, a structure in the brain where smell information from the nose is processed and sent to deeper regions of brain.
Minimally invasive retinal detachment treatment has better outcomes, clinical trial finds
A minimally invasive treatment for retinal detachment gives patients sharper vision, less distortion and reduced side-effects, according to the findings of a recent trial.
Underlying mechanisms of 3d tissue formation
Scientists utilize simulations and laboratory experiments to find that cells sense the mechanical forces to form the primordial eye, the optic cup.
Scientists develop 'contact lens' patch to treat eye diseases
Scientists have developed a 'contact lens' patch with microneedles that could be a painless and efficient alternative to current methods of treating eye diseases such as glaucoma. Patients are unable to keep up with the prescribed regime of current localized treatment methods like eye drops, which are hindered by the eye's natural defenses, blinking and tears. Eye injections can be painful and carry an infection risk and eye damage.
Eyes of Creutzfeldt-Jakob disease patients show evidence of prions
By the time symptoms of sporadic Creutzfeldt-Jakob disease (sCJD) are typically discovered, death is looming and inevitable. In a new study, researchers report finding tell-tale evidence of the condition's infectious agent in the eyes of deceased sCJD patients, making the eye a potential source for both early CJD detection and prevention of disease transmission.
Light scalpel: A major step toward non-viral ocular gene therapy using laser and nanotechnology
Gold nanoparticles, which act like 'nanolenses,' concentrate the energy produced by the extremely short pulse of a femtosecond laser to create a nanoscale incision on the surface of the eye's retina cells. This technology, which preserves cell integrity, can be used to effectively inject drugs or genes into specific areas of the eye, offering new hope to people with glaucoma, retinitis or macular degeneration.
Dry eye syndrome slows reading rate, study suggests
Researchers report that chronic dry eye, a condition in which natural tears fail to adequately lubricate the eyes, can slow reading rate and significantly disrupt day to day tasks that require visual concentration for long periods of time.
View of the retina in unprecedented detail
By combining two imaging modalities -- adaptive optics and angiography -- investigators can see live neurons, epithelial cells, and blood vessels deep in the eye's light-sensing retina. Resolving these tissues and cells in the outermost region of the retina in such unprecedented detail promises to transform the detection and treatment of diseases such as age-related macular degeneration (AMD), a leading cause of blindness among the elderly.
Spread of deadly eye cancer halted in cells and animals
By comparing genetic sequences in the eye tumors of children whose cancers spread with tumors that didn't spread, researchers report new evidence that a domino effect in cells is responsible for the cancer spreading.
Exosomes 'swarm' to protect against bacteria inhaled through the nose
A research team describes a newly discovered mechanism. The findings shed new light on our immune systems -- and also pave the way for drug delivery techniques to be developed that harness this natural transportation process from one group of cells to another.
Giant leap toward personalized medicine helps eyes drain themselves
Researchers created a new smart drainage device to help patients with glaucoma, a leading cause of blindness in the world, as they try to save their eyesight.
Traditional glaucoma test can miss severity of disease
The most common test for glaucoma can underestimate the severity of the condition by not detecting the presence of central vision loss, also known as macular degeneration, according to a new study.
Some of retina's light-sensing cells may have ancient roots
Scientists say they have identified what may be an ancient light-sensing mechanism in modern mouse retinal cells.
Novel strategy appears to protect retina when disease reduces oxygen
An enzyme known to help our liver get rid of ammonia also appears to be good at protecting our retina, scientists report.
Summer birth and computer games linked to heightened short-sight risk in childhood
Summer birth and hours spent playing computer games are linked to a heightened risk of developing short or near sightedness (myopia) in childhood, indicates a twin study.
Brain-computer interface advances improve prosthetics, therapies
Advances in connecting neural stimulation to physical control of the body are transforming the development of prosthetics and therapeutic training for people with disabilities, according to new research.
Novel mutation affecting YARS causes multisystem disease
Researchers have identified a novel missense mutation in tyrosyl-tRNA synthetase (YARS c.499C>A, p.Pro167Thr) that causes a severe recessive disorder in affected individuals. The report includes detailed clinical characterization of seven related Amish children who were homozygous for the variant. The children all exhibited poor growth, developmental delay, abnormal brain white matter, hearing loss, involuntary eye movements, progressive cholestatic liver disease, pancreatic insufficiency, hypoglycemia, anemia, intermittent excess of protein in urine, recurrent bloodstream infections, and chronic pulmonary disease.
Evidence of restored vision in rats following cell transplant
Researchers have discovered that neurons located in the vision centers of the brains of blind rats functioned normally following fetal retina cell transplants, indicating the successful restoration of vision.
New study offers hope for patients suffering from a rare form of blindness
A new form of therapy may halt or even reverse a form of progressive vision loss that, until now, has inevitably led to blindness. This hyper-targeted approach offers hope to individuals living with spinocerebellar ataxia type 7 (SCA7) and validates a new form of therapy with the potential to treat neurogenetic diseases effectively and with far fewer side effects than other medications.
3 (or more) spooky ways to trick your brain this Halloween
Did you really see that pale face just now? What was that sound? This Halloween, test the limits of your brain with these easy spooky experiments.
Babies born at home have more diverse, beneficial bacteria, study finds
Infants born at home have more diverse bacteria in their guts and feces, which may affect their developing immunity and metabolism, according to a new study.
Diabetes medication may protect against a common cause of blindness
Researchers have shown that people with type 2 diabetes who took a common diabetes medication, metformin, had a significantly lower rate of age-related macular degeneration (AMD).
Evidence mounts that an eye scan may detect early Alzheimer's disease
Results from two studies show that a new, non-invasive imaging device can see signs of Alzheimer's disease in a matter of seconds. The researchers show that the small blood vessels in the retina at the back of the eye are altered in patients with Alzheimer's.
Link between what we see and how we remember 'breaks' as we get older
Forgetfulness and age-related memory lapses are a common complaint among older adults, but what is still not understood is what causes these changes. Recent research brings us a step closer to uncovering the answer, which could help with distinguishing signs of dementia earlier.
Easier treatment for blinding eye disease shows promise in clinical trial
A new study shows that an implantable delivery system for a widely used medication to treat a blinding eye disease has enabled some patients to go 15 months in between treatments. This represents a vast improvement over the typical regimen of nearly monthly eye injections.
Biologists use 'mini retinas' to better understand connection between eye and brain
Biologists are growing 'mini retinas' in the lab from stem cells to mimic the growth of the human retina. The researchers hope to restore sight when critical connections between the eye and the brain are damaged. These models also allow researchers to better understand how cells in the retina develop and are organized.
Hallucinations associated with brain hyperactivity in people with macular degeneration
New research shows for the first time that visual hallucinations in people with macular degeneration are associated with abnormally heightened activity in the visual cortex of the brain. The findings could improve diagnosis of such hallucinations.
Surprising network activity in the immature brain
One of the outstanding mysteries of the cerebral cortex is how individual neurons develop the proper synaptic connections to form large-scale, distributed networks. Now scientists have gained novel insights from spontaneously generated patterns of activity by local networks in the early developing visual cortex. Apparently these form the basis for long-range neural connections that are established through brain activity over the course of cortical development.
Biomarkers facilitate early detection of glaucoma
Researchers have identified new potential biomarkers that may facilitate early detection of glaucoma in patients. Moreover, they ascertained that the mutation of a certain gene in mice causes intraocular pressure elevation. This, in turn, is one of the main risk factors for glaucoma.
New devices to test retinal cells
Researchers have developed new devices to better understand the triggers of age-related macular degeneration (AMD) by mechanically stressing cells.
Eating leafy greens could help prevent macular degeneration
A new study has shown that eating vegetable nitrates, found mainly in green leafy vegetables and beetroot, could help reduce your risk of developing early-stage age-related macular degeneration (AMD).
To track how students ace the LSAT, watch their eyes
Neuroscientists are tracking eye movements to understand how practicing tough reasoning tests like the LSAT makes students smarter.
How do you treat a droopy eyelid?
Ptosis refers to a droopy eyelid, where the upper eye area lowers downward. Causes include genetics, eye surgery, and excessive rubbing. Treatment can involve surgery, but usually for cosmetic reasons only. Prevention is harder due to genes playing a role. Learn more about this manageable condition here.
Discovery of a simplest mechanism for color detection
Color vision, ocular color detection is achieved with complicated neural mechanisms in the eyes. Researchers have found color detection with a simplest mechanism in the fish pineal organ, an extraocular photosensitive organ on the brain surface.
Abnormal vision in childhood can affect brain functions
A research team has discovered that abnormal vision in childhood can affect the development of higher-level brain areas responsible for things such as attention.
What is this white spot on my eyeball?
A white spot on the eye is often a corneal ulcer or a pinguecula. These eye conditions are treatable. It is essential to seek immediate medical attention for a white spot on the eye, as long-lasting damage can occur without treatment. Learn more about white spots on the eye, their causes, and treatment options here.
How the grid cell system of the brain maps mental spaces
How exactly the grid cell system works in the human brain, and in particular with which temporal dynamics, has until now been speculation. A much-discussed possibility is that the signals from these cells create maps of 'cognitive spaces' in which humans mentally organize and store the complexities of their internal and external environments. A team of scientists has now been able to demonstrate, with electrophysiological evidence, the existence of grid-like activity in the human brain.
How do hearing and sight influence cognitive decline?
Hearing and sight loss are tied to faster cognitive decline, so does addressing these issues slow down cognitive deterioration? New studies investigate.
Human retinas grown in a dish explain how color vision develops
Biologists grew human retina tissue from scratch to determine how cells that allow people to see in color are made.
Color-changing contact lens could enhance monitoring of eye disease treatments
For all the good they do, eye drops and ointments have one major drawback: It's hard to tell how much of the medication is actually getting to the eye. Now scientists report that they have developed a contact lens that changes color as drugs are released. This visual indicator could help eye doctors and patients readily determine whether these medications are where they should be.
Drugs could one day treat nearsightedness, reveals gene study
The molecular pathways involved in the development of near- and farsightedness are different, according to an animal study of gene changes in the retina.
Risk of blindness among premature babies with low levels of blood platelets
New research finds that premature babies with low levels of platelets (thrombocytes) in their blood run a greatly increased risk of being afflicted with a severe variation of retinopathy of prematurity (ROP), an eye disease that can cause blindness.
Gene changes driving myopia reveal new focus for drug development
Myopia (nearsightedness) and hyperopia (farsightedness) develop through different molecular pathways, according to a new study. The finding provides a new understanding of myopia, the most common form of visual impairment worldwide, and opens the way for development of drugs to prevent it.
Can Viagra permanently damage vision?
A case study examines the damage that Viagra can potentially do to the retina. In doses above recommended levels, the blue pill might make you see red.
Comparing nocturnal and diurnal rodents helps scientists understand a human eye disease
By venturing beyond the lab mouse to study the eyes of diurnal small mammals, scientists have uncovered a difference in the composition of rod and cone cell membranes that may explain how a genetic form of macular dystrophy targets only parts of the retina.
Some chiropractic treatments can harm eyesight
A new case study warns that certain chiropractic techniques can lead to problems with vision due to their direct effect on the eye's retina.
Irreversible damage to color vision linked to popular erectile dysfunction drug
Color vision problems caused by retinal damage on a cellular level can result from a high dose of sildenafil citrate, new research shows.
Mediterranean diet prevents a leading cause of blindness, study suggests
Evidence is mounting that a poor diet plays an important role in the development of age-related macular degeneration (AMD), a leading cause of blindness in the United States.
Can chiropractic care disrupt vision?
For those in the habit of getting their neck adjusted by a chiropractor, there's an interesting case to know about: High velocity neck manipulation has been shown to create stress on the eye and lead to spotty vision.
Most effective treatment approaches for uveitic macular edema
Injections of corticosteroids directly into the eye are superior to those placed adjacent to the eye for treating uveitic macular edema, one of the leading causes of blindness in the United States, a new research study has found.
Exploring links between senses and cognitive health
Experts are examining the link between impaired vision, hearing, and cognition.
Eye infection in contact lens wearers can cause blindness
A new outbreak of a rare but preventable eye infection that can cause blindness, has been identified in contact lens wearers in a new study. The research team found a threefold increase in Acanthamoeba keratitis since 2011 in South-East England.
What are the early signs of MS?
The early signs and symptoms of MS can vary widely, and some can be significantly challenging or debilitating. Here, learn more about the early symptoms of MS, such as vision problems and numbness, and when to consult a doctor.
Heartbeat paces learning, study finds
A new study shows that the processing of external information varies during the phases of the cardiac cycle.
Developmental stage for No. 1 eye tumor in children
Investigators have been able to pinpoint the exact stage of development of the human retina, when cells can grow out of control and form cancer-like masses. The finding could open the door for future interventions in retinoblastoma (RB), a tumor of the retina that affects children under five years of age.
Counting (on) sheep? Promising gene therapy for visually impaired sheep now safe for human trials
A promising gene therapy for visually impaired sheep is now safe for human trials.
A potential new way to treat some of the most common blinding diseases
Many eye diseases exhibit increased permeability of blood vessels in the macular portion of the retina leading to abnormal fluid accumulation and vision loss. Therapies targeting a specific cytokine, VEGF, have transformed clinical care; however, not all patients respond well. A new report shows that inhibiting a specific signaling molecule, atypical protein kinase C reduces increased vessel permeability and blocks inflammation. Blocking aPKC may help protect vision in potentially blinding eye diseases.
Eye movements take edge off traumatic memories
Two human experiments demonstrate that a widely used yet controversial psychotherapy technique suppresses fear-related amygdala activity during recall of a traumatic memory.
A first step toward cracking the genetics of strabismus
While some rare forms of strabismus have been linked to specific genes, common forms have been hard to pin down genetically. A new genome-wide association study, based on 10 years of work enrolling and studying families with esotropia (cross-eye) is the first step.
Facial plastic surgeons call for reduction of opioid prescriptions after rhinoplasty
A team of surgeons found that, of 173 patients undergoing rhinoplasty, a common procedure performed in the facial plastic and reconstructive surgery field, only two refilled their opioid prescriptions after the procedure -- with some patients not filling their initial opioid prescription at all.
Weak point in deadly eye melanoma identified
A natural plant compound exploits a newly identified Achilles' heel in a cancer of the eye, uveal melanoma. In human cancer cells growing in the lab, the compound shuts down the overactive signaling that drives uveal melanoma cell growth, according to researchers.
Attention network plays key role in restoring vision after brain damage
About one-third of patients who have suffered a stroke end up with low vision, losing up to half of their visual field. This partial blindness was long considered irreversible, but recent studies have shown that vision training after optic nerve and brain damage can help restore or improve vision. A new study reports on key mechanisms of vision restoration: attention.
Better assessments for early AMD
The European MACUSTAR consortium is conducting a multi-country clinical study on age-related macular degeneration. The clinical study focuses on the intermediate stage of the disease, in which a person's vision under low-light and low-contrast conditions is impaired. Throughout Europe, a total of 20 study centers will recruit and follow-up with 750 patients.
What are the benefits of pistachios?
Pistachios are nuts that offer numerous health benefits. These benefits include eye health, gut health, and high protein content that may be beneficial for dieting. They are also full of antioxidants and good for blood sugar balance. Learn more about the health benefits of pistachios, and some common myths, here.
Artificial intelligence can deliver specialty-level diagnosis in primary care setting, study shows
A system that uses artificial intelligence (AI) to detect diabetic retinopathy without a person interpreting the results earned Food and Drug Administration (FDA) authorization in April, following a clinical trial in primary care offices. The study was the first to prospectively assess the safety of an autonomous AI system in patient care settings.
New urine dipstick test detects cause of disease that blinds millions
Scientists have developed a urine diagnostic to detect the parasitic worms that cause river blindness, also called onchocerciasis, a tropical disease that afflicts 18 to 120 million people worldwide.
How can shingles affect the eyes?
Shingles is a common infection that can affect every part of the body, including the eyes. Shingles can cause vision problems, drooping of the eyelid, and, in some cases, vision loss. Here, we examine the effects of shingles on the eye. We also describe tips for prevention and the available treatment options.
Handheld probe images photoreceptors in children
Researchers have developed a handheld probe that can image individual photoreceptors in the eyes of infants. The technology, based on adaptive optics, will make it easier for physicians and researchers to observe these cells to diagnosis eye diseases and make early detection of brain-related diseases and trauma.
Alzheimer's one day may be predicted during eye exam
Using technology similar to what is found in many eye doctors' offices, researchers have detected evidence suggesting Alzheimer's in older patients who had no symptoms of the disease.
Knockdown and replace: A gene therapy twofer to treat blindness
More than 150 different mutations in the light-sensing molecule rhodopsin can cause retinitis pigmentosa, characterized by a progressive loss of night and peripheral vision. A team has now developed a treatment for the condition. Successful results in dogs set the stage for testing in humans.
A new generation of artificial retinas based on 2D materials
Scientists report they have successfully developed and tested the world's first ultrathin artificial retina that could vastly improve on existing implantable visualization technology for the blind. The flexible 2-D material-based device could someday restore sight to the millions of people with retinal diseases.
The eyes may have it, an early sign of Parkinson's disease
The eyes may be a window to the brain for people with early Parkinson's disease. People with the disease gradually lose brain cells that produce dopamine, a substance that helps control movement. Now a new study has found that the thinning of the retina, the lining of nerve cells in the back of the eye, is linked to the loss of such brain cells.
Congenital blindness reversed in mice
Researchers have reversed congenital blindness in mice by changing supportive cells in the retina called Müller glia into rod photoreceptors. The findings advance efforts toward regenerative therapies for blinding diseases such as age-related macular degeneration and retinitis pigmentosa.
Ethiopian 7-year trial finds that childhood eye infection increases after antibiotic program ends
Continuous mass distribution of azithromycin in northern Ethiopia, where the childhood eye infection trachoma is a major cause of blindness, is effective in preventing recurrence of trachoma but does not eliminate the infection entirely.
Vision loss in glaucoma may be due to immune response
Glaucoma is a condition that leads to progressive loss of vision, but its root causes remain unclear. New research says an immune response may be to blame.
How people adapt to post stroke visual impairments
A new study examines the factors that influence how a person adapts to visual field loss following stroke.
Glaucoma may be an autoimmune disease
A new study finds glaucoma may be an autoimmune disorder, mediated by T cells that target heat shock proteins in the retina. The discovery suggests it could be possible to develop new treatments for glaucoma by blocking this autoimmune activity.
More than half of drivers don't look for cyclists and pedestrians before turning right
Researchers studied the eye movements of drivers at busy Toronto intersections and found that more than half failed to make necessary scans for pedestrians or cyclists at right turns. This is the first study to date that used eye-tracking equipment to accurately assess where drivers were looking when turning at an intersection.
Chemists discover how blue light from digital devices speeds blindness
Blue light from digital devices and the sun transforms vital molecules in the eye's retina into cell killers, according to optical chemistry research.
Eye conditions provide new lens screening for Alzheimer's disease
A study of 3,877 randomly selected patients found a significant link between three degenerative eye diseases -- age-related macular degeneration, diabetic retinopathy and glaucoma -- and Alzheimer' disease.
Genetic factors contributing to 'strabismus' -- or misaligned eyes
Researchers have discovered a key gene for generating eye movements. Using zebrafish, they developed a compelling model system to analyze the brain-eye muscle connections, and found that the brain neurons use repulsive forces mediated by a protein encoded by the protocadherin 17 gene to position properly and reach the target eye muscle. The findings potentially contribute to treatment of congenital eye movement disorders.
Scientists determine the structure of a lipid that keeps our tears clear
Researchers report the structure of a key long-chain lipid in the tear film lipid layer, which prevents tears from drying out. Their finding may be used to improve treatments for dry eye.
Injection of vasoactive intestinal peptide into the eye improves corneal transplant survival
A new study reports for the first time that injection of neuropeptide vasoactive intestinal peptide (VIP) directly into the eye of mice enhanced corneal graft survival.
What are the health benefits of goji berries?
Goji berries are used in traditional medicine for their health benefits. Several scientific studies back some of their purported health-giving properties, which include fighting eye diseases and cancer and promoting healthy skin. Learn more about the scientific evidence behind the benefits of goji berries here.
Is too much screen time harming children's vision?
Does digital eyestrain cause lasting damage to children's eyes? Should your child use reading glasses or computer glasses?
Google Glass helps kids with autism read facial expressions, study finds
Children with autism were able to improve their social skills by using a smartphone app paired with Google Glass to help them understand the emotions conveyed in people's facial expressions, according to a pilot study.
What role do immune cells play in dry eye?
Dry eye and inflammation that arise from disruption of moisturizing oil glands in the eyelids could be due to blockage by immune cells, a new study finds.
How a turmeric compound could treat glaucoma
Glaucoma can lead to vision loss, but a turmeric derivative can improve current treatments. New research devises a viable method of adding it to eye drops.
Turmeric-derived eye drops could treat glaucoma: study
A derivative of turmeric could be used in eye drops to treat the early stages of glaucoma, a new study finds.
Saliva test could improve diabetes control and treatment
A simple saliva sample could replace blood tests to assess and monitor diabetes, finds a new study. The most comprehensive analysis of proteins in saliva to date finds that these proteins reflect high blood sugar and associated disease processes in children and adolescents with uncontrolled type 1 diabetes, long before the appearance of clinical symptoms. This could lead to better prediction and prevention of long-term complications of the disease.
Blindness gene discovered
Researchers have investigated a recessive genetic disorder that destroys the eyes from developing and results in childhood blindness. After analyzing the genomes of each member of a consanguineous family with affected children, the geneticists pinpointed pathogenic mutations in a new gene, MARK3, as being the cause. They subsequently confirmed their findings by modifying the homologous gene in drosophila flies, which resulted in abnormal eye development and blindness.
Gene regulator may contribute to protein pileup in exfoliation glaucoma
In exfoliation glaucoma, a protein dandruff clogs the outflow pathway for the fluid in our eyes. Scientists have evidence that variants of the same gene that enables us to make connective tissue by crosslinking proteins is associated with this unusual glaucoma.
Researchers are one step closer to developing eye drops to treat common sight loss condition
Scientists are one step closer to developing an eye drop that could revolutionise treatment for age-related macular degeneration (AMD).
New retinal ganglion cell subtypes emerge from single-cell RNA sequencing
Single-cell sequencing technologies are filling in fine details in the catalog of life. Researchers have now identified 40 subtypes of retinal ganglion cells (RGCs) along with the genetic markers and transcription factors that differentiate them.
What causes a blocked tear duct in infants?
A blocked tear duct is very common in babies. There are many possible causes, including tear ducts that are too narrow. Symptoms include excessive watering of the eyes. Most cases do not cause any pain and do not require treatment. Learn more about the causes and treatment of a blocked tear duct in a baby here.
Variations of a single gene drive diverse pigeon feather patterns
Biologists have discovered that different versions of a single gene, called NDP (Norrie Disease Protein), have unexpected links between color patterns in pigeons, and vision defects in humans. These gene variations were likely bred into pigeons by humans from a different pigeon species and are now evolutionarily advantageous in wild populations of feral pigeons living in urban environments.
Chemicals associated with oxidative stress may be essential to development
Some level of molecules linked to oxidative stress may be essential to health and development, according to new animal studies.
An orange a day keeps macular degeneration away: 15-year study
A new study has shown that people who regularly eat oranges are less likely to develop macular degeneration than people who do not eat oranges. Researchers interviewed more than 2,000 Australian adults aged over 50 and followed them over a 15-year period.
Children with better coordination more likely to achieve at school
Young children with better eye-to-hand coordination were more likely to achieve higher scores for reading, writing and math according to new research -- raising the possibility schools could provide extra support to children who are clumsy.
Scientists visualize the connections between eye and brain
Researchers have developed a means of tracking the activity of the far-reaching ends of retinal neurons (called boutons) as they deliver visual information to the thalamus, a brain region involved in image processing.
Function of a mysterious component of the inner ear revealed
A new study finds that a mysterious component of the inner ear acts as a pressure-relief valve, formed by a thin barrier of cellular projections that opens and closes to regulate the release of inner ear fluid.
Injectable electronics offer powerful new tool in understanding how retinal cells work
For decades, scientists hoping to understand how the retina interprets visual input have often had to resort to invasive techniques to dissect the retina from the animal in an effort to record the cells' activity, but a new system could make it possible to track the firing patterns of dozens of cells chronically in awake animals.
New nerve gas detector built with Legos and a smartphone
Researchers have designed a way to sense dangerous chemicals using, in part, a simple rig consisting of a smartphone and a box made from Lego bricks, which could help first responders and scientists in the field identify deadly and difficult-to-detect nerve agents such as VX and sarin.
What is a slit lamp exam?
A slit lamp exam is a routine procedure where a doctor shines a light into the eye to look for injuries or diseases. These may include a detached retina, corneal abrasion, or cataracts. Abnormal results can also indicate infection, inflammation, or increased eye pressure. Learn more about the slit lamp exam here.
How to get debris out of your eye
Getting an object stuck in the eye is a common problem. It does not usually cause lasting damage, but it is essential to remove it to avoid scratching the cornea. Here, learn how to remove a foreign object from the eye safely at home. If a sharp or fast-moving object enters a person’s eye, they should see a doctor.
Important step towards a computer model that predicts the outcome of eye diseases
Understanding how the retina transforms images into signals that the brain can interpret would not only result in insights into brain computations, but could also be useful for medicine. As machine learning and artificial intelligence develop, eye diseases will soon be described in terms of the perturbations of computations performed by the retina. A newly developed model of the retina can predict with high precision the outcome of a defined perturbation.
Fundamental rule of brain plasticity
A series of complex experiments in the visual cortex of mice has yielded a simple rule about plasticity: When a synapse strengthens, others immediately nearby weaken.
Persistent stress may lead to vision loss, study shows
A new analysis of existing studies shows that persistent psychological stress can lead to conditions such as glaucoma, retinal neuropathy, and vision loss.
Obesity in childhood and adulthood shown to increase risk of knee and hip osteoarthritis
A new study suggests that childhood and adult obesity increase the risk of developing hip osteoarthritis (OA) and knee OA but not hand OA.
161 genetic factors for myopia identified
Myopia, also known as short-sightedness or near-sightedness, is the most common disorder affecting the eyesight and it is on the increase. This is particularly worrying for severely short-sighted people as it increases their risk of developing eyesight complications. The causes are both genetic and environmental.
The curious case of a blind woman who sees motion
The brain's ability to rewire itself, or neuroplasticity, explains the case of a blind woman who can see objects only when they are in motion.
Neuronal activity sheds light on the origin of consciousness
A new study identifies and measures the neural activity associated with a new conscious experience. It takes researchers a step closer to solving the mystery of consciousness.
Researchers map brain of blind patient who can see motion
Since the visual processing centres of her brain went dark after a stroke, a Scottish woman has been unable to see objects. However, she has developed the remarkable ability to see objects in motion, neuroscientists at Western University in Canada have discovered.
Novel system mimics focus activity of the human eye
A new computational system effectively mimics the natural way the human eye corrects focus, specifically while viewing objects that are closer rather than farther away.
New method can quickly and accurately detect infections
Two chemistry researchers have developed a method that can show quickly and accurately whether a person has been infected with harmful bacteria or other pathogens. Additionally, this new method shows the exact severity of infection in a person.
Normal eye dominance is not necessary for restoring visual acuity in amblyopia
Research published today may lead to changes in how amblyopia is treated, particularly in adults. The research shows that eye dominance and visual acuity are controlled by different areas of the brain, and that one can be corrected without correcting the other.
Education may lead to short-sightedness
New research offers 'strong evidence' that the more years someone spends in full time education, the more likely they are to become short-sighted.
Sensor detects whiff of bad breath
Ever wish you could do a quick "breath check" before an important meeting or a big date? Now researchers have developed a sensor that detects tiny amounts of hydrogen sulfide gas, the compound responsible for bad breath, in human exhalations.
Increased electrical activity in eye may relieve short-term dry eye pain
A boost of electrical activity in the eye's mucous membranes may lead to new treatments for the painful condition known as dry eye.
Decades of type 1 diabetes linked to mild drop in cognition
People who live with type 1 diabetes for very long duration show signs of mild decreases in cognitive abilities, primarily in memory, compared to those who don't have the disease.
Preventable deaths from lack of high-quality medical care cost trillions
Eight million largely preventable deaths from treatable diseases cost $6 trillion in lost economic welfare in low- and middle-income countries in 2015. If current conditions persist, low- and middle-income countries could lose collectively $11 trillion in gross domestic product by 2030, or 2.6 percent of total GDP in low-income countries.
The health effect of air pollution from traffic
What would happen if all petrol and diesel-powered vehicles were removed from a smaller European city? Up to 4% of all premature deaths could be prevented, according to a new study. The researchers used Malmö, Sweden, as a case study to calculate the health costs of inner city traffic.
What to know about punctal plugs for dry eye
Punctal plugs are small medical devices that doctors can insert into the tear ducts in a procedure called punctal occlusion. The plugs may be temporary or last many years, and they keep the eyes lubricated to improve dry eye symptoms. Here, learn about the punctal occlusion procedure, including possible side effects.
Broken eye socket: Symptoms, surgery, and recovery
A broken eye socket can occur if an accident or injury leads to an excessive force on the area around the eye. There are four different types of broken eye socket, which doctors categorize according to the part of the socket where the fracture occurs. In this article, learn more about symptoms, treatment, and recovery.
Dormant cytomegalovirus resides in eyes of healthy mice long after infection
Infection with cytomegalovirus triggers long-lasting eye inflammation and establishes a dormant pool of the virus in the eyes of mice with healthy immune systems, according to new research.
Promise of faster, more accessible schizophrenia diagnosis
A new study shows how the hand-held device RETeval may prove to be a more accessible way to diagnose schizophrenia, predict relapse and symptom severity, and assess treatment effectiveness.
First 3D-printed human corneas
The first human corneas have been 3D printed by scientists.
how the brain maintains attentional focus during eye movements
New findings reveal how the brain maintains attentional focus during eye movements. The research could lead to treatments and therapies for some brain disorders.
Noninvasive technique to correct vision
Engineers have developed a noninvasive approach to permanently correct vision that shows great promise in preclinical models. The method uses a femtosecond oscillator for selective and localized alteration of the biochemical and biomechanical properties of corneal tissue. The technique, which changes the tissue's macroscopic geometry, is non-surgical and has fewer side effects and limitations than those seen in refractive surgeries. The study could lead to treatment for myopia, hyperopia, astigmatism, and irregular astigmatism.
Can you use Botox under your eyes?
Botox is often used to treat lines and wrinkles around the eyes and mouth. Can it also reduce dark circles or bags under the eyes? Using Botox under the eyes is not approved in the U.S. and researchers are unsure how well it may work and what side effects may occur. Here, learn about the procedure and its alternatives.
New type of vertigo identified
Neurologists have identified a new type of vertigo with no known cause, according to a new study.
Adolescents with hay fever have higher rates of anxiety and depression
A new article shows allergies can have serious, far-reaching consequences, especially on adolescent sufferers.
Training compassion 'muscle' may boost brain's resilience to others' suffering
A new study suggests that as little as two weeks of compassion meditation training -- intentionally cultivating positive wishes to understand and relieve the suffering of others -- may reduce the distress a person feels when witnessing another's suffering. The findings may have implications for professions in which people routinely work with others who are suffering, like doctors, law enforcement officers and first responders.
Method to overcome false positives in CT imaging for lung cancer
A team of researchers has identified a technology to address the problem of false positives in CT-based lung cancer screening.
How Ebola affects the eye: Study provides further insight into
A new study identifies the specific characteristics of Ebola retinal lesions, which provide further clues as to how the virus travels to the retina and causes damage.
New computational strategy designed for more personalized cancer treatment
Mathematicians and cancer scientists have found a way to simplify complex biomolecular data about tumors, in principle making it easier to prescribe the appropriate treatment for a specific patient.
Forensics: New tool predicts eye, hair and skin color from a DNA sample of an unidentified individual
An international team has developed a novel tool to accurately predict eye, hair and skin color from human biological material -- even a small DNA sample -- left, for example, at a crime scene or obtained from archeological remains. This all-in-one pigmentation profile tool provides a physical description of the person in a way that has not previously been possible by generating all three pigment traits together using a freely available webtool.
How do you get rid of itchy eyes?
Itchy eyes at night can be bothersome and reduce a person's ability to sleep properly. Itching can also cause redness and swelling, which may continue into the daytime. Allergies, irritants, or even eyestrain may trigger them. There are many home remedies to try. Learn more about itchy eyes at night here.
Genome surgery for eye disease moves closer to reality
Researchers have developed a new technique for the powerful gene editing tool CRISPR to restore retinal function in mice afflicted by a degenerative retinal disease, retinitis pigmentosa. This is the first time researchers have successfully applied CRISPR technology to a type of inherited disease known as a dominant disorder. This same tool might work in hundreds of diseases, including Huntington's disease, Marfan syndrome, and corneal dystrophies.
What does it mean when your eyes are glassy?
When a person is tired, their eyes can become glassy or cloudy. In other cases, glassiness in one or both eyes can signal an underlying medical condition. Some, like conjunctivitis, require treatment and can be severe. In this article, learn why eyes become glassy, how the symptom is treated, and ways to prevent it.
How to get rid of yellow eyes
Yellow eyes can result from damage to the liver, pancreas, or gallbladder. These organs help to filter bilirubin, a yellow compound, from the blood. While most cases require medical attention, we look at whether home remedies can be safe and effective. Learn about the causes and treatments of yellow eyes here.
What causes burning eyes?
Burning eyes is stinging or irritation of the eyes. They can be uncomfortable and concerning. Treatment depends upon identifying the underlying cause. Common causes include dry eyes, allergies, and sun exposure. Here, we look at the different causes of burning eyes and how to treat them, including home remedies.
Ophthalmologists link immunotherapy with a serious eye condition
Eye inflammation and uveal effusion develop among patients taking anti-cancer immune checkpoint inhibitor therapy.
Can the eyes really turn purple?
Alexandria's genesis is a fake condition that began in 2005 with a rumor spread online. Supposedly, a genetic mutation can turn a person into a "perfect" being with purple eyes. We describe this myth and real conditions that can alter the color of the eyes. Learn why eye color may change and when to see a doctor here.
What causes mucus strands in the eyes?
Mucus fishing syndrome is a condition where a person continually fishes excess strands of mucus from the surface of their eye. Constantly removing the mucus can cause further irritation. Causes include conjunctivitis, dry eye, and physical irritation. Learn more about causes and treatments for mucus fishing syndrome.
Organic printing inks may restore sight to blind people
A simple retinal prosthesis is under development. Fabricated using cheap and widely-available organic pigments used in printing inks and cosmetics, it consists of tiny pixels like a digital camera sensor on a nanometric scale. Researchers hope that it can restore sight to blind people.
Strategy prevents blindness in mice with retinal degeneration
New research outlines a strategy that in mouse models significantly delayed the onset of blindness from inherited retinal degeneration such as retinitis pigmentosa.
New diagnostic technique picks up the S in vision
A new technique that could help improve diagnosis of vision disorders has been successfully tested.
What does eye herpes look like?
The herpes simplex virus that causes cold sores can also affect the eyes. Herpetic eye disease can lead to sores forming on the eyelid, light sensitivity, and may affect vision. In this article, we examine the ways that herpes affects the eyes and what treatments are available to bring relief.
Is it possible to change your eye color?
A person may want to change their eye color for cosmetic reasons or because they have a condition that alters the pigmentation of the iris. In this article, we describe temporary and permanent ways to change eye color. Also, learn how the tint of the iris develops and why it may shift naturally over time.
Causes and treatment for dilated pupils
Mydriasis refers to dilated pupils that do not change in response to changes in light levels. Some medications, recreational drugs, and injuries can cause this. The opposite, pinpoint pupils, is called miosis. In this article, we talk about the possible causes for mydriasis and some of the treatments available.
Butterfly wings inspire light-manipulating surface for medical implants
Nanostructures inspired by transparent butterfly wings help eye implants function better and safely avoid biofouling.
Dark chocolate may boost vision
Researchers have set their sights on dark chocolate as a potential vision booster, after finding that the delicious treat may improve eyesight.
New development in contact lenses for red-green color blindness using simple dye
Researchers have developed a contact lens that may help people with color blindness simply by using a low cost dye.
How to safely flush your eye
If chemicals come into contact with the eye, it is essential to flush them out immediately. In this article, we describe how to flush the eyes using clean water or a solution. We also explain what to do if an object becomes lodged in the eye. Learn how to remove irritants and prevent further damage here.
New tools in the fight against diabetic blindness
Estimates are that 600 million people will have some sort of diabetic retinopathy by 2040. Previously, no good animal models existed that scientists could use to study the disease, its diagnosis or potential treatments. Now, scientists have employed a mouse model exhibiting diabetic retinopathy symptoms that could lead to future translational research studies.
What causes bumps on the eyeball?
Finding a bump on the eyeball can be alarming, but most causes are harmless and easily treatable. In this article, we look at issues that can cause a bump to form, including a stye and a scratched cornea. We also describe types of bumps. Here, learn about treatment, home care, and how to prevent bumps from reoccurring.
Glowing contact lens could prevent a leading cause of blindness
A glow-in-the-dark contact lens could help stave off blindness in the hundreds of millions of people who suffer from diabetes across the globe.
Watch your step: How vision leads locomotion
Using new technologies to track how vision guides foot placement, researchers come one step closer in determining what is going on in the brain while we walk, paving the way for better treatment for mobility impairments -- strokes, aging and Parkinson's -- and technology development -- prosthetics and robots.
Why is my eyelash growing in the wrong direction?
Instead of becoming trapped under the skin, an ingrown eyelash may grow in the wrong direction, toward the eye. This is called trichiasis, and it can cause irritation, pain, and damage to the cornea. Injury, inflammation, or certain conditions may be responsible. Medical treatment is often necessary. Learn more here.
How long are you contagious with pink eye?
Pink eye is a relatively common eye condition. There are many potential causes, but one of the most significant problems is how not to spread the condition to others. There are different types of pink eye, which can change the length of contagiousness. Knowing the signs can help a person avoid infecting anybody else.
Frog embryos can fully regrow their eyes after injury, debunking a belief that they can't
Scientists have found that frog embryos can fully regrow their eyes after injuries, a breakthrough that may lead one day to the ability to orchestrate tissue regeneration in humans.
Does the 20-20-20 rule prevent eye strain?
The 20-20-20 rule says that after spending 20 minutes on the computer, a person should spend 20 seconds looking at an object 20 feet away. This may help to prevent eyes from becoming dry or watery. Here, learn why the 20-20-20 rule is effective. We also describe other ways to protect the eyes from digital strain.
What happens if you sleep with your eyes open?
People sometimes sleep with their eyes open, which is known medically as nocturnal lagophthalmos. Symptoms caused by this condition include redness and blurry vision. Treatment options include eye drops, moisture goggles, or even surgery. It does not usually have serious complications. Learn more about it here.
Omega-3s from fish oil supplements no better than placebo for dry eye
Omega-3 fatty acid supplements taken orally proved no better than placebo at relieving symptoms or signs of dry eye, according to the findings of a well-controlled trial.
Scientists teach computers how to analyze brain cells
In the early days of neuroscience research, scientists painstakingly stained brain cells and drew by hand what they saw in a microscope. Fast forward to 2018 and machines may be able to learn how to do that work. According to a new study, it may be possible to teach machines how to pick out features in neurons and other cells that have not been stained or undergone other damaging treatments.
New glaucoma treatment could ease symptoms while you sleep
Eye drops could one day treat glaucoma while you sleep -- helping to heal a condition that is one of the leading causes of blindness around the world.
Telemedicine provides accurate diagnosis of rare cause of blindness in preemies
Accurately detecting a rare, but devastating cause of blindness in premature babies can be done as effectively with telemedicine as with traditional, in-person eye exams, a study suggests. The finding could enable more blindness-preventing treatment for infants born in rural and other areas where there are few ophthalmologists trained to detect the condition, called retinopathy of prematurity, or ROP.
Unexpected finding may deter disabling diabetic eye disease
A new study is the first to find that a particular type of lipid, or fat, thought to only exist in the skin, now lives in your eye and might play a major role in deterring diabetic retinopathy.
Brain differences in athletes playing contact vs. Noncontact sports
A study has found differences in the brains of athletes who participate in contact sports compared to those who participate in non-contact sports.
Macular degeneration linked to aging immune cells
Studying mice and cells from patients, vision researchers found that as immune cells called macrophages get older, they are more likely to contribute to inflammation and abnormal blood vessel growth in the back of the eye. This can damage vision in patients with age-related macular degeneration.
Post-Ebola cataract surgery can safely restore vision
Cataract surgery can be safely performed on Ebola virus disease survivors with impaired vision, researchers report.
Retinal implant designed to replace support cells damaged by dry age-related macular degeneration
Researchers have published preliminary results of a first-in-human clinical trial for dry age-related macular degeneration (AMD). Four patients received implants consisting of human embryonic stem cell-derived retinal pigment epithelium (RPE), which support light-sensitive photoreceptor cells critical to vision.
Watching brain cells interacting in real time
An advance by neuroscientists could lead to a better understanding of astrocytes, a star-shaped brain cell believed to play a key role in neurological disorders like Lou Gehrig's, Alzheimer's and Huntington's disease.
Mifepristone may halt growth of intracranial tumor that causes hearing loss
Researchers have shown that mifepristone, a drug currently FDA-approved for chemical abortion, prevents the growth of vestibular schwannoma (also known as acoustic neuroma) cells. This sometimes-lethal intracranial tumor typically causes hearing loss and tinnitus.
What to know about sulfa allergies
A sulfa allergy is when the immune system reacts to substances containing sulfa, such as some antibiotics and medications. A person with a sulfa allergy should avoid certain medications but does not need to avoid any specific foods. Learn how sulfa and sulfite allergies differ, and about symptoms and treatment.
New method speeds up 3-D printing of millimeter-sized imaging lenses
Researchers ahve used 3-D printing to make high-quality customized lenses quickly and at low-cost, which could be used for optical imaging, vision correction, and disease diagnosis.
Mitochondrial disease patients face difficult road to diagnosis
A new study documents the prolonged and difficult path patients face before they are diagnosed with mitochondrial diseases, a group of rare, debilitating genetic disorders.
Half of vision impairment in first world is preventable
Around half of vision impairment in Western Europe is preventable, according to a new study.
Microorganisms can escape from a dead end by swimming
Researchers have shown that microorganisms can ingeniously escape from a dead end by swimming. The results pave the way to understanding the spread of infectious diseases.
Toward precision medicine: First comprehensive look at human retinal cell diversity
In work that brings researchers closer to the goal of precision medicine approaches to treating glaucoma and other neurodegenerative vision diseases, a new study has, for the first time, been able to identify a wide variety of previously unknown cell subtypes in the human eye.
Administering antibiotics through the cornea
Researchers have developed ocular inserts which allow a patient's cornea to absorb more antibiotics than current methods.
Immune cells in the retina can spontaneously regenerate
Immune cells called microglia can completely repopulate themselves in the retina after being nearly eliminated, according to a new study in mice. The findings point to potential therapies for controlling inflammation and slowing progression of rare retinal diseases such as retinitis pigmentosa (RP) and age-related macular degeneration (AMD).
Role of specific gene in 16p11.2 deletion autism
New findings in mice suggest that the lack of a copy of the gene MVP may contribute to the symptoms of 16p11.2 deletion syndrome because it is needed for brain circuits to incorporate changes driven by experience.
What does it mean when you see stars?
Many people say they “see stars” when they are seeing flashes of light in their field of vision. Learn about what causes these visual disturbances.
Stem cells treat macular degeneration
Researchers have developed a specially engineered retinal patch to treat people with sudden, severe sight loss.
Top ten foods for healthy eyes
Foods rich in certain nutrients can have a powerful effect on eye health. Read about 10 foods for healthy eyes, other eye health tips, and warning signs.
Seven causes of pinpoint pupils
Pinpoint pupils are pupils that remain very small even in bright light. They can signify many issues, including drug use, poisoning, or a hemorrhage.
Optometrist investigates changes in eye structure in astronauts
An optometrist studies the vision of returning International Space Station astronauts and demonstrates a structural change to their eyes.
Google's AI program: Building better algorithms for detecting eye disease
A new study lays important groundwork for an automated system that can detect diabetic eye disease.
'Digistain' technology offers revolution in detailed cancer diagnosis
New cutting edge technology can be used to grade cancer tumors, eradicating human subjectivity and ensuring patients get the right treatment, researchers say.
Why is my eyebrow twitching?
Eyebrow twitching may result from everyday factors, such as caffeine, or disorders such as hemifacial spasm. Learn about causes and when to see a doctor.
Mapping the genome jungle: Unique animal traits could offer insight into human disease
An interdisciplinary team of scientists are using animals' unique traits to pinpoint regions of the human genome that might affect health.
Overlooked cell key player in preventing age-related vision loss
Researchers have pinpointed a new therapeutic target for macular degeneration, an eye disease that affects over 10 million Americans and is the leading cause of blindness in adults over 60. The findings show that tree-shaped retinal cells called Müller glia play a key role in preventing degenerative vision loss in rats.
New gene therapy corrects a form of inherited macular degeneration in canine model
Researchers have developed a gene therapy that successfully treats a form of macular degeneration in a canine model. The work sets the stage for translating the findings into a human therapy for an inherited disease that results in a progressive loss of central vision and which is currently untreatable.
Eye infection: A gentle approach treating microbial keratitis
Microbial infections of the cornea can have serious consequences, including blindness in the worst case. The treatment of keratitis, a condition caused by certain pathogens, always presents major challenges to ophthalmologists. These corneal infections frequently cannot be successfully treated with the therapies currently available. Researchers are pursuing a new approach: contact lenses with germicidal properties could offer an alternative to conventional therapies. Initial tests in the laboratory and on donor corneas were successful.
Nerve damage in type 2 diabetes can be detected in the eye
By examining the cornea of the eye with a special microscope it may be possible within ten minutes to diagnose if a person with type 2 diabetes has nerve damage.
Can our eyes help predict who will develop memory loss?
People whose eyes show signs of small changes in blood vessels at age 60 may be more likely to develop thinking and memory problems by the time they are 80 than people with healthy eyes, according to a new study.
'Social brain' networks are altered at a young age in autism
As infants develop, they respond to social cues such as voices, faces and gestures. Their brain develops a network of regions that specialise in translating these cues, the 'social brain'. A common observation in infants later diagnosed with Autism Spectrum Disorders is reduced sensitivity towards these social cues. A team of researchers from the University of Geneva brings evidence of how this phenomenon hinders the normal development of the social brain at early developmental stages.
Eleven causes of pain when blinking
Some people have a painful sensation when they blink, which may have a range of causes. Learn more about the reasons for it and how to get rid of it here.
New directions found in understanding, fighting glaucoma
Two distinctive handfuls of short molecules that regulate gene expression have been found in the eye fluid of patients with two distinct types of vision degenerating glaucoma.
Metalens combined with an artificial muscle
Inspired by the human eye, researchers have developed an adaptive metalens that is essentially a flat, electronically controlled artificial eye. The adaptive metalens simultaneously controls for three of the major contributors to blurry images: focus, astigmatism, and image shift.
How to identify and treat eyelid dermatitis
Learn about the types of eyelid dermatitis, and how to get rid of these itchy rashes. We also look at symptoms, causes, and prevention.
Neurons fight back early in brain disease
A therapeutic target to preserve vision in glaucoma patients could have treatment ramifications for age-related neurodegenerative disorders like Alzheimer's and Parkinson's, according to new findings.
Artificial intelligence quickly and accurately diagnoses eye diseases and pneumonia
Using artificial intelligence and machine learning techniques, researchers have developed a new computational tool to screen patients with common but blinding retinal diseases, potentially speeding diagnoses and treatment.
New smart contact lens for diabetics introduced
A team of researchers has developed a new biosensing contact lens capable of detecting glucose levels in patients with diabetes.
Creative couples' intervention significantly helps people with Alzheimer's communicate
For couples with decades of shared memories, a partner's decline in the ability to communicate because of dementia is frightening and frustrating. Communication strategies they've used before simply don't work anymore. By getting creative, an in-home intervention to support couples affected by dementia is showing that 'practice does make perfect,' both for the caregiver and the care receiver or person with dementia, and can improve their communication behaviors in just 10 weeks.
Very long-chain lipids could help prevent dry eye disease
Very long-chain lipids in the most superficial layer of the tear film cause severe dry eye disease when they were shortened in mice -- a result that could help develop new drugs for the disease.
Shot may help shield against shingles
Two vaccines are available to help prevent shingles, which can affect anyone who has had chickenpox or the chickenpox vaccine; both diseases are caused by the same virus, which stays in the body after chickenpox clears.
What causes a buildup of pressure behind the eyes?
In this article, we look at reasons for feelings of pressure behind the eye, including a migraine or sinus infection. When should you see a doctor?
A new class of drug to treat herpes simplex virus infection
For patients with the herpes simplex-1 virus (HSV-1), there are just a handful of drugs available to treat the painful condition that can affect the eyes, mouth and genitals. If patients develop resistance to these drugs, there are even fewer choices left to treat the infection, which lasts for life. Researchers have now identified a small drug molecule that can clear the HSV-1 infection in the cells of the cornea -- the clear outer layer of the eyeball -- and works completely differently than the currently-available drugs, making it a promising potential option for patients who have developed resistance.
Eye exams linked to kids' reading levels
Elementary school children who read below grade level may have challenges with their eyesight even if standard tests show they see 20/20, according to a new study.
Can't get an image out of your head? Your eyes are helping to keep it there.
Through brain imaging, scientists have found evidence that the brain uses eye movements to help people recall vivid moments from the past, paving the way for the development of visual tests that could alert doctors earlier about those at risk for neurodegenerative illnesses.
In effort to treat rare blinding disease, researchers turn stem cells into blood vessels
People with a mutated ATF6 gene have a malformed or missing fovea, the eye region responsible for detailed vision. From birth, vision is severely limited, and there is no cure. Researchers were the first to link ATF6 to this type of vision impairment. In a new study, the team discovered that a chemical that activates ATF6 converts patient stem cells into blood vessels.
New device measures blink reflex parameters to quickly and objectively identify concussion
A new device offers a valid, reliable tool for identifying concussion head injuries, researchers report. Comparing blink reflex parameters in football players suspected of having sustained a concussion to healthy players revealed specific, significant differences. Noninvasive and quick to collect, blink reflex data provide objective support for concussion-related decisions and may be useful in other neurological disorders.
Oregon woman first known case of human infected with cattle eyeworm species
A 26-year-old Oregon woman was the first known case of a human being infected with the cattle eyeworm Thelazia gulosa, which normally affects large animals. She was likely infected while being around cows near her rural home, experts conclude.
How do you get rid of puffy eyes?
A look at periorbital edema, a condition where swelling around the eyes causes them to appear puffy. Included is detail on diagnosis and the outlook.
New discovery offers hope of protecting premature babies from blindness
Now there is hope of a new way to protect extremely premature babies from impaired vision or blindness resulting from the eye disease retinopathy of prematurity (ROP). A study points to a clear link between ROP and low levels of the fatty acid arachidonic acid, measured in children's blood.
Everything you need to know about papilledema
A look at papilledema, a condition where the optic nerve becomes swollen. Included is detail on the outlook and how to get a diagnosis.
Eye could provide 'window to the brain' after stroke
Research into curious bright spots in the eyes on stroke patients' brain images could one day alter the way these individuals are assessed and treated. A team of scientists has found that a chemical routinely given to stroke patients undergoing brain scans can leak into their eyes, highlighting those areas and potentially providing insight into their strokes.
Could looking into the eyes aid stroke diagnosis?
A contrast agent given to stroke survivors undergoing MRI brain scans can leak into the eyes and may help to improve diagnosis and treatment.
Diabetes doubles chance of developing cataract
People with diabetes are twice as likely to develop cataract as the general population and the relative risk is highest in those aged between 45 and 54, according to a new study.
Balance exercises may help people with multiple sclerosis
A special program that involves balance and eye movement exercises may help people with multiple sclerosis (MS) with their balance problems and fatigue, according to a new study.
What causes eye boogers?
Eye boogers are mucus, a type of discharge that helps to keep the eyes clean and free of debris. Learn more about eye boogers in this article.
What is this bump on my eyelid?
Learn all about the different types of bump that can appear on the eyelids. This article examines their causes and treatment options.
Eye and heart complications are tightly linked in type 1 diabetes
People with chronic kidney disease have much higher risk of cardiovascular disease, the leading cause of death for those with type 1 diabetes. In a new article researchers demonstrated that the eye condition known as proliferative diabetic retinopathy also is independently associated with cardiovascular disease.
Novel periodic autoinflammatory syndrome: It's all about the eyes
Scientists have identified a new genetic mutation that alters the function of cryopyrin and leads to a life-long periodic inflammation of the cornea, the transparent window of the human eye. Patients who carry the mutation also develop corneal opacities that compromise vision.
Retinal injury caused by laser pointers
In recent years, a substantial increase in the number of eye injuries caused by laser pointers has been observed, especially in children and adolescents. Researchers report sometimes severe retinal injuries and irreversible impairments to vision/visual acuity.
Too few with stroke of the eye are treated to reduce future stroke
Only one-third of 5,600 patients with retinal infarction, or stroke in the eye, underwent basic stroke work-up, and fewer than one in 10 were seen by a neurologist. One in 100 of the retinal infarction patients studied experienced another stroke within 90 days of their retinal infarction.
Genetic link between thinner corneas and increased risk of glaucoma
Genetic studies in mice point to a protein called POU6F2, which can modulate corneal thickness, as a possible risk factor for glaucoma in humans, researchers report.
The eye is not immune to immunity
Contrary to long-established dogma, the eye can host an active immune response that could both heal injury and contribute to loss of vision.
Viral probe gives ringside view of cell-to-cell combat
A fascinating blow-by-blow account of the arms struggle between plants and viral pathogens, is revealed in new research.
When the eyes move, the eardrums move, too
Simply moving the eyes triggers the eardrums to move too, even in the absence of sound, says a new study by neuroscientists. The findings, which were replicated in both humans and rhesus monkeys, provide new insight into how the brain coordinates what we see and what we hear. It may also lead to new understanding of hearing disorders, such as difficulty following a conversation in a crowded room.
Reduced attention to audiovisual synchrony in infancy predicts autism diagnosis
An ability to integrate information from different sensory modalities is important for infants' development and for their perception of the environment. A new study suggests that infants who pay little attention to synchronous sights and sounds may be at elevated risk for developing autism spectrum disorder (ASD).
New instrument lets doctors view the entire eye with unprecedented level of detail
Researchers have developed the first instrument that can provide a detailed image of the entire eye that can produce higher quality images than currently available.
Efficacy of antibody targeting Devic's disease proven in new animal model
Neuromyelitis optica (NMO) is an autoimmune disease associated with NMO immunoglobulin G (NMO-IgG). A cure for NMO remains elusive. Researchers recently established a localized NMO rat model by injecting NMO-IgG into the spinal cord, and assessed the efficacy of anti-repulsive guidance molecule-a (RGMa) antibody in treating NMO. They found anti-RGMa antibody delayed the onset and attenuated the severity of clinical symptoms of NMO, suggesting that humanized anti-RGMa antibody is a potentially valid therapeutic approach for NMO.
Statins to help prevent scar tissue in the eye?
According to a new study, statin medication seems to reduce the risk of repeated surgery in patients who undergo a vitrectomy to treat a detached retina. The researchers believe that statins might prevent the formation of scar tissue inside the eye.
Study advances gene therapy for glaucoma
A new study has shown an improved tactic for delivering new genes into the eye's fluid drain, called the trabecular meshwork. It could lead to a treatment for glaucoma.
Five tips for healthy sight
Are you worried about your eyes? We have compiled some top tips to help you maintain healthy sight, boost eye health, and prevent eye-related diseases.
What to know about central serous retinopathy
A look at central serous retinopathy, a condition where the retina detaches and causes vision loss. Included is detail on risk factors, and diagnosis.
An introduction to eyes and how they work
The eyes are incredibly complex organs. In this article, we explain their anatomy, how they work, and describe some conditions that affect the eyes.
Biologists peek into the past to see the future through tiny spider eyes
Biologists look to the past for early genetic development of tiny spider and insect eyes to find potential for research into human visual challenges.
New discovery may explain winter weight gain
We may have a new reason, in addition to vitamin D generation, to bask in a little sunshine. A breakthrough has shown the fat cells that lie just beneath our skin shrink when exposed to the blue light emitted by the sun.
Illnesses caused by recreation on the water costs $2.9 billion annually in the US
Swimming, paddling, boating and fishing account for more than 90 million cases of gastrointestinal, respiratory, ear, eye and skin-related illnesses per year in the US with an estimated annual cost of $2.9 billion, according to a new report.
All you should know about Waardenburg syndrome
A look at Waardenburg syndrome, a group of diseases that cause changes in the body and eye color. Find out about how rare it is and the diagnosis.
Large increase in non-powder gun-related eye injuries
A study investigated sports- and recreation-related eye injuries during a 23-year period and found a slight decrease in eye injuries overall; however, the rate of eye injury associated with non-powder guns (including BB, pellet and paintball guns) increased by almost 170 percent.
Study: Sleeping sickness not just a sleeping disorder
An international study shows one of Africa's most lethal diseases is actually a circadian rhythm disorder caused by the acceleration of biological clocks controlling a range of vital functions besides sleep.
Discovery brings stem cell therapy for eye disease closer to the clinic
Scientists report that tiny tube-like protrusions called primary cilia on cells of the retinal pigment epithelium (RPE) -- a layer of cells in the back of the eye -- are essential for the survival of the retina's light-sensing photoreceptors. The discovery has advanced efforts to make stem cell-derived RPE for transplantation into patients with geographic atrophy, otherwise known as dry age-related macular degeneration (AMD), a leading cause of blindness in the US.
Diabetic blindness caused and reversed 'trapped' immune cells in rodent retinas
Researchers have discovered a cell signaling pathway in mice that triggers vision loss in patients with diabetic retinopathy and retinal vein occlusion – diseases characterized by the closure of blood vessels in the retina, leading to blindness. In experiments that suppressed vascular endothelial growth factor (VEGF) in the eye, researchers were able to re-establish normal blood flow in the retina, offering a potential means of stalling or even reversing diabetes-related blindness.
What is optic neuritis?
Learn all about optic neuritis, a condition where the optic nerve is inflamed. This article looks at the symptoms, treatments, and causes.
Short-term exercise equals big-time brain boost
Even a short burst of exercise can temporarily boost our brain power, says a new study.
Protein analysis allows for treatment of eye-disease symptoms with existing drugs
Demonstrating the potential of precision health, a team of researchers has matched existing drugs to errant proteins expressed by patients with a rare eye disease.
What is keratitis?
Learn more about inflammation of the cornea, also known as keratitis. We examine its different causes, along with symptoms and treatment options.
Could a cup of hot tea each day reduce the risk of glaucoma?
Glaucoma, an eye condition that can lead to blindness, affects a significant number of older adults. Could a household beverage help to shield us from it?
What you should know about rose water
A look at rose water, a liquid made using water and rose petals. Included is detail on the types of rose water and the side effects of using it.
Uhthoff's phenomenon: What you need to know
Uhthoff’s phenomenon is when changes in body temperature make a person’s existing MS symptoms worse. Learn about the triggers and how to cope.
All you should know about sunken eyes
A look at the condition of sunken eyes, where the eyes seem deep set and darkened. Included is detail on home remedies and when to see a doctor.
Exercise may protect you from glaucoma
The results of a new study show that people who engage in moderate- to vigorous-intensity exercise have a 73 percent lower risk of developing glaucoma.
What is a basilar migraine?
Basilar migraines can cause severe pain and are often accompanied by visual disturbances. Learn more about their diagnosis and how to cope.
What you need to know about esotropia
A look at esotropia, a condition that causes the eyes to turn inward. Included is detail on the common causes and how the condition is diagnosed.
What is a heliotrope rash?
A heliotrope rash may appear as a purple rash on or around the eyelids. Learn more about the causes and risk factors of this rash.
Cataract surgery tied to lower risk of death in older women
An analysis of Women's Health Initiative data has found that cataract surgery is tied to a lower overall and cause-specific risk of death in older women.
Protein discovery may improve treatments for diabetic eye disease
A new study shows how a protein called ARF6 is involved in the development of diabetic retinopathy, and that inhibiting it may lead to new treatments.
How does arthritis affect the eyes?
While arthritis is known to cause inflammation in the joints, it can also cause problems in the eyes. Learn about the causes, symptoms, and treatments.
Tips to control crying
A look at how to stop crying. Included is information on how to control crying with both mental and physical approaches, and how to avoid triggers.
All you need to know about epiretinal membrane
A look at the condition epiretinal membranes (ERMs). We examine the risk factors and complications, along with how to prevent the condition, here.
Brown, blue, green, and hazel: What is the secret behind eye color?
Human eyes display an impressive color palette, ranging from dark brown through shades of green, and to light blue. But what determines these unique hues?
Pseudophakia (IOL): Signs you need them and complications
When do you need artificial lenses for the eyes? Find out here along with more information on the specific types and how they are implanted.
Vitrectomy: Procedure, complications, and recovery
Learn more about vitrectomy, a procedure that involves removing fluid from the eye. We look at why it may be needed, and the risks and complications.
Benefits of crying: Why it's good to shed a few tears
Crying is a natural and often uncontrollable reaction we have to sadness, grief, joy, and pain. Is crying good for your health? Find out.
Natural protein may help to prevent blindness
Researchers have shed light on the mechanisms underlying glaucoma, a leading cause of blindness, which could lead to new treatments for the disease.
Arcus senilis: Causes, symptoms, and treatment
In this article, learn about arcus senilis. What are the risk factors, how is it diagnosed, how is it linked to high cholesterol, and can it be treated?
Researchers identify potential biomarkers of age-related macular degeneration
Findings may lead to earlier diagnoses and better prognostic information for patients - and, potentially, new pharmaceutical targets for AMD treatment.
Central heterochromia (two different eye colors): Causes and types
Central heterochromia occurs when a person has different colors in the same eye. Variations in the spread and concentration of skin pigment cause this.
Blindness study shows how gene causes middle-age sight loss
Chemical changes in the eye that can lead to blindness have been identified by scientists.
Eyelashes: The eyeball's flirtatious bodyguards
Eyelashes might look pretty, but they also have a serious job: to keep dust away from our eyes. If they are too long, they can no longer fulfill this role.
Antioxidant/zinc supplement cost saving and effective for degenerative eye disease
A supplement that combines antioxidants with zinc and copper is a relatively inexpensive and effective means of halting the progression of a certain type of degenerative eye disease, concludes...
Scientists discover common diabetes drug reduces sight-threatening rise in brain pressure
Research led by the University of Birmingham, UK, published in Science Translational Medicine, shows that a GLP-1 agonist drug, currently used to treat patients with Type II diabetes could be...
How an eye test could detect Alzheimer's
Researchers reveal how a novel imaging technique could diagnose Alzheimer's disease by detecting beta-amyloid plaques in the retinas of patients.
Color blindness: When red looks like brown
From street signs to our national flags, colors are an integral part of society. But for colorblind individuals, this can cause serious challenges.
Visual impairment among older adults associated with poor cognitive function
In a nationally representative sample of older U.S. adults, visual impairment was associated with worse cognitive function, according to a study published by JAMA Ophthalmology.
Why do onions make us cry?
Few can escape the wrath of the onion; the chemicals released in self-defense make us well up. Scientists shed light on the enzyme responsible.
Marcus Gunn pupil: Causes, diagnosis, and treatment
Marcus Gunn pupil is a condition affecting the eyes. In this article, learn about the causes, symptoms, and treatment options for Marcus Gunn pupil.
Demyelination: Causes, symptoms, and treatments
Demyelination is damage to the myelin layer, or the protective coating of nerve cells. This can lead to neurological problems including slow reflexes.
Dacryocystitis: Causes, symptoms, and treatment
What is dacryocystitis? In this article, learn about the causes of this infection that affects the tear ducts, how it is diagnosed, and treatment.
Laser treatment reduces eye floaters
Patients reported improvement in symptoms of eye floaters after treatment with a laser, according to a study published by JAMA Ophthalmology.
Homocystinuria: Causes, symptoms, and tests
What is homocystinuria? In this article, learn about the causes of this condition and who it affects, the symptoms, and how it is diagnosed and treated.
Researchers identify visual system changes that may signal Parkinson's disease
Changes in the visual systems of newly diagnosed Parkinson's disease patients may provide important biomarkers for the early detection and monitoring of the disease, according to a new study...
Eye microbiome trains immune cells to fend off pathogens
Microbe living on the surface of the eye protects cornea from infections.Bugs in your eyes may be a good thing.
Eyelid twitch: Common causes, treatment, and prevention
An eyelid twitch can be very frustrating, especially when it is an ongoing problem. Learn about the possible causes of eyelid twitch, and how to treat it.
Sufferers of both Type 2 diabetes and sleep apnoea could lose eyesight within four years
Research led by the University of Birmingham has discovered that patients who suffer from both Type 2 diabetes and obstructive sleep apnoea are at greater risk of developing a condition that leads to...
What makes eyes itch?
Summer is here, and allergies are rearing their ugly heads, causing many an itchy eye. Find out what happens in your eye to bring you such distress.
Swollen eyelid: Twelve causes and treatments
Twelve of the most common causes of swollen eyelid. In this article, learn about why swollen eyelids occur, how to prevent them, and how to treat symptoms.
Magnetic implants used to treat 'dancing eyes'
A research team has successfully used magnets implanted behind a person's eyes to treat nystagmus, a condition characterised by involuntary eye movements.
Histoplasmosis: Causes, risk factors, and treatment
Histoplasmosis is a fungal infection with a variety of flu-like symptoms. Although it is not contagious, it can cause chronic complications. Learn more.
Is your doctor prescribing the wrong treatment for pink eye?
Ophthalmologists urge practitioners to stop overprescribing antibiotics for a common eye infection that typically clears up without medication.
Dressmakers found to have needle-sharp 3-D vision
Study finds seamstresses possess stereoscopic superpowers.Haute couture can be credited for enhancing more than catwalks and red carpets.
Eye stroke: Symptoms, risks, and treatment
In this article, learn about what an eye stroke is. How is an eye stroke diagnosed, how can it be prevented, and what treatment is available?
Competitive football players have superior vision, study suggests
The visual abilities of competitive football players are substantially better than those of healthy non-athletes, according to the first-ever comprehensive assessment of visual function in English...
Light-responsive ligands activate retinal neurons to repair vision loss in blind mice
Retinitis pigmentosa, age-related macular degeneration, and other retinal diseases lead to the deterioration of photoreceptors, the light-sensing cells in the eye.
Are soft contact lenses safe for children? Risks seem no higher than in adults
Available evidence suggests that soft contact lenses can be safely prescribed to children and adolescents, with no increase in adverse effects compared to adults, according to a review in Optometry...
Eyesight continues to develop until your 40s, new study finds
The findings may have repercussions for people with amblyopia or other eye disorders that are currently only being treated in childhood.
Identical twins have identical vision, down to the smallest detail
A study finds that identical twins are identical down to the tiniest defects in their eyes. Genes have more control over vision than initially thought.
Switching to a low-glycemic diet may stop age-related eye disease, study suggests
A study in mice finds that development of age-related macular degeneration (AMD) could be arrested by switching from a high-glycemic diet (starches as are found in white bread) to a low-glycemic...
Wet AMD: Small trial shows new gene therapy is safe in humans
A new gene therapy that neutralizes the growth factor that promotes wet AMD is shown to be safe and well tolerated in a small trial of human patients.
University of Birmingham develops revolutionary eye drops to treat age-related blindness
Scientists at the University of Birmingham have developed a type of eye drop which could potentially revolutionise the treatment of one of the leading causes of blindness in the UK.
Diabetes doctors: Which specialists treat diabetes?
There are a variety of healthcare professionals that can help manage diabetes. Knowing what to expect from each will help you make the most of your visit.
Avastin as effective as Eylea for treating central retinal vein occlusion
Monthly eye injections of Avastin (bevacizumab) are as effective as the more expensive drug Eylea (aflibercept) for the treatment of central retinal vein occlusion (CRVO), according to a clinical...
Prevalence of visual impairment among preschool children projected to increase
The number of preschool children in the U.S. with visual impairment is projected to increase by more than 25 percent in the coming decades, with the majority of visual impairment resulting from...
Disfiguring eye symptoms diminish in Graves' eye disease drug trial
The disease is characterized by inflammation and a buildup of tissue around the eyes that cause them to bulge painfully from their sockets.
Findings suggest underdiagnosis of AMD not uncommon in primary eye care
Approximately 25 percent of eyes deemed to be normal based on dilated eye examination by a primary eye care ophthalmologist or optometrist had macular characteristics that indicated age-related...
Clinical trial discovers a new way to prevent children with arthritis and eye disease losing their sight
A trial funded by the charity Arthritis Research UK and the National Institute for Health Research (NIHR) has discovered a drug combination that could help thousands of children with arthritis.
New eye test detects earliest signs of glaucoma
A simple eye test could help solve the biggest global cause of irreversible blindness, glaucoma.
Researchers identify new target for abnormal blood vessel growth in the eyes
A team led by Massachusetts Eye and Ear researchers has identified a novel therapeutic target for retinal neovascularization, or abnormal blood vessel growth in the retina, a hallmark of advanced...
New chemical composition of 'poppers' linked to retinal damage
The new chemical composition of the legal high 'poppers' is linked to retinal damage at the back of the eye, finds a small study published online in the British Journal of Ophthalmology.
Fish eyes to help understand human inherited blindness
Discovery of a gene in zebrafish that triggers congenital blindness could lead to a suitable cure for similar disease in humans.
Marker may help predict success with extended-wear contact lenses
A simple marker on eye examination may help vision care professionals predict which patients will have a higher or lower rate of problems after starting extended-wear contact lenses, reports a...
This chemical reaction in eye can boost your vision | The Siasat Daily
Washington: A team of researchers has discovered a chemical reaction in the eye that may improve vision. A light-sensing pigment found in everything from bacteria to vertebrates can be biochemically manipulated to reset itself, an important therapeutic advantage, according to the research from Case Western Reserve University School of Medicine. Researchers successfully used a modified form of vitamin A, called locked retinal, to induce the recycling mechanism and engage proteins central to human vision. The targeted proteins include light-sensing rhodopsin, which belongs to a family of proteins, G protein-coupled receptors, or GPCRs, that sit in cell membranes and transmit external cellular cues into internal cell signaling pathways. The discovery opens a new therapeutic opportunity for modified retinals that help improve vision, and offers a major improvement over current therapeutics designed to perturb cell signaling in the eye. “Our study demonstrates a complete transition from a one-way activation of a GPCR into a self-renewing, recycling activation mechanism by the mere addition of a cyclohexyl chemical group to the retinal. These findings exemplify the possibility of reprogramming GPCRs into self-renewing machines that can be controlled by external cues. This biochemically induced function will be helpful in treating people with vision impairment, and opens up several avenues for more efficient GPCR-based therapeutics,” said first author Sahil Gulati.
Specks in your vision can signal serious eye conditions
These "floaters" are not just bothersome. They can be signs of potential retinal disease. Floaters, those tiny specks that drift across your field of vision, are usually harmless and often disappear or become less noticeable on their own. But sometimes they indicate a condition that can lead to vision loss. "A new onset of floaters may herald retinal disease," says Dr. Jeffrey Heier, director of the retina service at Ophthalmic Consultants of Boston and clinical instructor in ophthalmology at Harvard Medical School. If the vitreous detaches, it may pull on the retina and cause a tear. This may cause blood to ooze into the vitreous gel, and a person will see black spots or floaters. Without treatment, progression from a tear to a retinal detachment could cause permanent vision loss....
Study finds ethnic differences in effect of age-related macular degeneration on visual function
In study that included Chinese, Malay, and Indian participants, researchers found that among those with age-related macular degeneration (AMD) there were ethnic differences in visual function, such...
In Australia, the bionic eye comes into focus
Just a few months after receiving $42 million from the Australian government, Bionic Vision Australia (BVA) unveils its prototype bionic eye, which researchers hope will enable users to perceive points of light that the brain can reconstruct into images. Announced this week at the University of Melbourne, the wide-view neurostimulator concept was developed by researchers at BVA and the University of New South Wales for patients with vision loss due to retinitis pigmentosa or macular degeneration. The set-up includes a video camera mounted to glasses to capture images, a wireless processor to convert and send those images to the implant, and a chip with 98 electrodes that is attached to the retina. When the implant receives signals from the processor, it stimulates the optic nerve, which directs the electrical impulses from the retina to the brain's visual center. "We anticipate that this retinal implant will provide users with increased mobility and independence," said Anthony Burkitt, BVA's research director and an engineering professor at the University of Melbourne. Retinal implants were recently hailed as a success in a human trial by German company Retinal Implant. Leighton Boyd, who was diagnosed with retinitis pigmentosa at age five and is now president of Retina Australia, hopes to be an implant recipient in the near future. The prototype could be ready for human trial as early as 2011. BVA is already talking up the prototype's second-gen model, a higher-def implant that might enable users to read large print and recognize faces. They hope to have it ready for testing in four years.
New technique helps treat glaucoma case
When Amar Agarwal, chairman, Dr. Agarwal’s Eye Hospital, was operating on 83-year-old Sulochana Erady for glaucoma, he realised that the usual laser technique, in which an opening is created to let the fluid from the eye drain, would not work. “She had closed angle glaucoma, and it was impossible to use a laser, as it would have affected the cornea. That is when we decided to do something new — single-pass four throw (SFT) pupilloplasty,” he said. Speaking to the press on Saturday, Dr. Agarwal said the technique had been used for the first time to treat closed angle glaucoma in Ms. Sulochana. “The technique involves pulling the iris from the angle where it is attached, suturing it in place and creating a clear angle for the fluid in the eye (aqueous humour) to drain out. The suture is looped only once around the iris and knotted, rather than the usual three times, which means that the iris can be dilated for other treatment if necessary,” he said.
6 Surprising signs your eyes reveals about your health
The role the eyes plays in your life can't be overemphasized. One of such roles is alerting you about your health status. So if anything changes in your eyes, you immediately take notice. It may not be just any change. These eye problems may be alerting you to some crucial health conditions that you must not ignore. In line with this,Jumia travel, the leading online travel agency, identifies the things your eyes says about your health. Try to pay attention to these signs.
Study suggests new way to prevent vision loss in diabetics and premature babies
Researchers at Bascom Palmer Eye Institute, part of the University of Miami Miller School of Medicine, have identified a new molecule that induces the formation of abnormal blood vessels in the...
Itchy eyes: Causes and treatment options
How can you relieve itchy or dry eyes? When should you see a doctor? Learn about common causes of this irritating condition and how to manage symptoms.
How blind people's brains rewire to improve other senses
Breaking research shows how the brains of blind people are naturally rewired to compensate for the lack of visual input, boosting the remaining senses.
Repeated eye injections for age-related macular degeneration associated with increased risk for glaucoma surgery
Patients with age-related macular degeneration who received seven or more eye injections of the drug bevacizumab annually had a higher risk of having glaucoma surgery, according to a study...
Unproven stem cell 'therapy' blinds three patients at Florida clinic
Three people with macular degeneration were blinded after undergoing an unproven stem cell treatment that was touted as a clinical trial in 2015 at a clinic in Florida.
Changes of the cell environment are associated with certain eye diseases
In case of ischemic injury to the retina, changes occur in the protein scaffold in the environment of retinal cells, the so-called extracellular matrix.
New nano-implant could one day help restore sight: With high-resolution retinal prosthesis built from nanowires and wireless electronics, engineers are one step closer to restoring neurons' ability to respond to light
They detail their work in a recent issue of the Journal of Neural Engineering. The technology could help tens of millions of people worldwide suffering from neurodegenerative diseases that affect eyesight, including macular degeneration, retinitis pigmentosa and loss of vision due to diabetes. ...
Fighting blindness: TSRI scientists bring a key protein into focus
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have discovered how a protein called α2δ4 establishes proper vision.
Rabbits' detached retina 'glued' with new hydrogel
A newly developed elastic gel administered in liquid form and shown to turn jellylike within minutes after injection into rabbits' eyes to replace the clear gelatinous fluid inside their eyeballs...
Eyes hold clues to future narrowing of leg vessels
Changes in tiny blood vessels of the eye may predict a higher risk of later narrowing in the large blood vessels in the legs, according to a study.
Zebrafish study sheds light on the eye's ability to regenerate
A new study looks into the fish eyes' ability to regenerate after injury and uncovers the role of a neurotransmitter in triggering this process.
In-home occupational therapy curbs depression in visually impaired patients
Johns Hopkins researchers report that in-home occupational therapy appears to reduce the rate and severity of depression in people at higher risk for the disorder because of seriously impaired...
The Potential Of Nutrition To Save Sight
While 20/20 vision is a symbol of visual acuity, between now and the year 2020, more and more people will experience some extent of vision loss due to age-related macular degeneration (AMD) and other sight-robbing diseases. Now, Agricultural Research Service (ARS)-funded scientists at the Laboratory for Nutrition and Vision Research are finding that healthy eating can reduce not only health care costs, but also the decline of quality of life due to these diseases. The laboratory, directed by Allen Taylor, is part of the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University in Boston, Mass. One study indicated that regularly consuming a combination of protective nutrients and a low-glycemic-index, or "slow carb," diet provided an AMD protective effect. A food's glycemic index is an indicator of how fast the carbohydrate it contains will spike blood sugar levels. The macula is a 3-millimeter-wide yellow spot near the center of the retina responsible for the central field of vision. For the study, the researchers analyzed dietary intake and other data from more than 4,000 men and women, aged 55 to 80, who had participated in the long-term Age-Related Eye Disease Study, or AREDS. Led by Chung-Jung Chiu, the researchers ranked intake of each of several nutrients consumed during the AREDS study, then calculated a compound score to gauge their combined dietary effect on the risk of AMD. The scoring system allowed them to evaluate associations between individual - and combined - dietary nutrients.
New 'Lazy Eye' Treatment
Eye drops work just as well as eye patches and are less likely to be shunned by youngsters with lazy eye, the most common cause of visual impairment in children, a study shows. Parents often have difficulty getting youngsters to wear eye patches because of discomfort and teasing.But the study found children and parents preferred atropine drops and were more likely to use them than patches. "This may well become a new standard treatment for some forms of amblyopia," the medical name for lazy eye, said Dr. Paul A. Sieving, director of the National Eye Institute, which funded the study. The study, chaired by Dr. Michael Repka of Johns Hopkins University, found the drops worked as well as patches in treating mild to moderate forms of the disorder in children aged 3 to 6. More severe forms, when vision is worse than 20/100, may require patches. The condition causes poor vision in an otherwise healthy eye because the brain has learned to favor the other eye. Symptoms can include crossed eyes, farsightedness and nearsightedness. It affects as many as 3 percent of U.S. children and usually develops in infancy or early childhood, according to NEI. Standard treatment has been eye patches worn over the unaffected eye, which stimulates better vision in the "lazy" eye. The same thing happens with atropine drops, which temporarily blur vision in the unaffected eye.
Assessing the impact of stress in age-related macular degeneration
Age-related macular degeneration (AMD), the leading cause of vision loss among older adults in the United States, is often associated with psychological stress.
Red eyes: List of common causes
In this article, learn about the common causes of red eye, including conjunctivitis, corneal ulcer, dry eye syndrome, and subconjunctival hemorrhage.
Common causes of eye pain explained
In this article, learn about common causes of eye pain, such as corneal disorders, glaucoma, uveitis, and endophthalmitis. Also learn about eye care tips.
Youth with type 2 diabetes develop complications more often than type 1 peers
Teens and young adults with type 2 diabetes develop kidney, nerve, and eye diseases - as well as some risk factors for heart disease - more often than their peers with type 1 diabetes in the years...
World-first genetic clues point to risk of blindness
Australian scientists have discovered the first evidence of genes that cause Macular Telangiectasia type 2 (MacTel), a degenerative eye disease which leads to blindness and is currently incurable...
Schirmer's test: What to expect with the dry eye test
What is the Schirmer's test, why is the test used, and who should have a Schirmer's test? What should be expected and what do the results mean?
Best contact lenses for people with dry eyes
What type and brand of contact lens may be best for people with dry eyes? Are there any lifestyle changes that may help and are there any associated risks?
Vitamin B-3 successfully prevents glaucoma in mice
The research - led by Jackson Laboratory professor and Howard Hughes medical investigator Simon W.M. John - investigates the effect of vitamin B-3 on mice that had been genetically modified to be prone to developing glaucoma. The findings were published in the journal
Best Eye Drops for People With Red Eyes
What are the main causes of red eye and when should red eye be treated with eye drops? What drops are available and who should avoid eye drops? Most people experience red eyes at some point. The symptom is usually fleeting and annoying rather than long-lasting or dangerous. Over-the-counter or prescription drops can treat red eyes. It's important to determine why eyes are red before treating symptoms, however, since infections and some other medical issues can cause red eyes. When to treat red eyes with drops. In most cases, dry eyes are merely a cosmetic concern. It's fine to treat minor irritation, exhaustion, and occasional redness with eye drops. Over-the-counter eye drops may treat dry eye, but certain symptoms should be directed to a healthcare professional. People should note that anti-redness drops won't treat underlying problems. People will probably have to keep using them if the cause is not dealt with. Over-the-counter eye lubricating drops may treat and prevent minor dry eye, but prescription remedies tend to work better. When to see a doctor. People don't need to see a doctor every time their eyes are red. However, anyone who experiences any of the following symptoms will need medical treatment:
The importance of vision care for children
Vision care is extremely important for kids. 80% of all # Children use visuals in their learning development and when eyesight is strained or blurry, that can decrease a child's chances of advancement in learning. Quite often, children who have vision problems are misdiagnosed as having learning disabilities when in fact, it is an eye problem which could be remedied with glasses or other simple solutions. Parents should start taking their children to have vision tests while they are still infants. This should be a routine visit beginning at 6 months, and again at 3 years old as well as right before the child enters school for the first time. Having these routine visits can be the difference between permanent eye damage and normal healthy vision. Often, small children cannot verbally let parents know that they are having difficulty seeing. They tend to display vision problems with signs such as performing poorly in school, headaches, problems with reading or writing, not completing homework assignments on time, wanting to stay home from school, and displaying attention span problems. All of these issues can be signs of behaviour or learning disabilities and are quite often overlooked as a vision problem.
AI as good as ophthalmologists at diagnosing a rare eye condition
An artificial-intelligence (AI) algorithm performs just as well as individual ophthalmologists in diagnosing congenital cataracts, reports a paper published online in Nature Biomedical Engineering. The algorithm, which has been implemented as a cloud-based platform for multihospital collaboration, may also help to improve the management of other rare diseases. Convolutional neural networks - artificial networks with connectivity patterns inspired by the organization of the visual cortex - can accurately identify specific motifs in images when trained with massive amounts of curated data. However, such AI schemes have not been tested in the clinic when data is scarce, as is the case for rare diseases. Yizhi Liu and colleagues report the implementation of convolutional neural networks for the diagnosis of congenital cataracts - a rare disease that causes clouding of the eye lens and is responsible for about 10% of all vision loss in children worldwide. They used a set of 50 cases involving various challenging clinical situations, a needle-in-a-haystack test with a realistic ratio of disease-to-healthy cases, and 57 cases from a phase-I multihospital clinical trial involving infants. The authors show that the AI algorithm diagnosed the disease, identified its severity, and suggested treatment with overall accuracies exceeding 90%. ...
Drug-dispensing contact lens effectively lowers eye pressure in glaucoma model
A contact lens designed to deliver medication gradually to the eye could improve outcomes for patients with conditions requiring treatment with eye drops, which are often imprecise and difficult to self-administer. In a study published online in Ophthalmology, a team of researchers have shown that a novel contact lens-based system, which uses a strategically placed drug polymer film to deliver medication gradually to the eye, is at least as effective, and possibly more so, as daily latanoprost eye drops in a pre-clinical model for glaucoma. "We found that a lower-dose contact lens delivered the same amount of pressure reduction as the latanoprost drops, and a higher-dose lens, interestingly enough, had better pressure reduction than the drops in our small study," said first author Joseph B. Ciolino, M.D., an ophthalmologist at Massachusetts Eye and Ear and an Assistant Professor of Ophthalmology at Harvard Medical School. "Based on our preliminary data, the lenses have not only the potential to improve compliance for patients, but also the potential of providing better pressure reduction than the drops." Glaucoma is the leading cause of irreversible blindness in the world. While there is no cure for glaucoma, ocular medications aim to lower pressure in the eye with the goal of preventing vision loss. Currently, the medications are delivered as eye drops, which sometimes cause stinging and burning, can be difficult to self-administer and are subsequently associated with poor patient compliance, with some studies suggesting that compliance is as low as 50 percent.
Lighthouse Guild Offers Tips for Good Eye Health
Vision screenings and eye exams are critical to detect problems like amblyopia, or lazy eye, the most common cause of visual impairment among young children, according to the National Eye Institute. That's why experts, like the U.S. Preventive Services Task Force, recommend vision screening for all children at least once between ages 3 and 5 years. A pediatrician, family physician or other trained health care provider can conduct screenings, which are often offered at schools, community health centers or community events. If a vision problem is suspected, the next step should be an eye examination performed by an ophthalmologist or optometrist.
New peptide could improve treatment for vision-threatening disease
Johns Hopkins researchers report that a new peptide holds promise for improving treatment for degenerative retinal diseases, such as age-related macular degeneration, diabetic macular edema anddiabetic retinopathy. These vascular diseases often result in central vision loss as blood vessels grow into tissues at the back of the eye, where such growth should not occur. The study, published in Science Translational Medicine, shows that the injectable peptide may more strongly suppress abnormal blood vessel growth and leakage in the eye, cause regression of established abnormal vessels, and may last longer when compared to current treatments. If proven effective in humans, this could mean that patients need only a few needle injections to the eye per year, instead of the monthly injections that are the current standard of care. Aflibercept is the standard treatment for these retinal diseases and specifically targets one protein, vascular endothelial growth factor (VEGF), which signals for the production of these new problematic blood vessels. Treatments are administered by injecting drugs that bind VEGF directly into the eye. "The production of VEGF is chronic, so repeated injections every four to six weeks is needed in most patients, often indefinitely," says Peter Campochiaro, M.D., the George S. and Dolores D. Eccles Professor of Ophthalmology at the Johns Hopkins University School of Medicine.
iStent helps relieve eye pressure for glaucoma patients: “Smallest device approved for implantation”
MILWAUKEE — Glaucoma is a common and chronic disease that affects a person’s vision. There are several ways of treating glaucoma, but there’s an innovative new option for patients that reduces eye pressure, and a Milwaukee eye surgeon is one of the few in the area trained to do the procedure.Karen Goodstein loves to travel. She and her husband Aaron have traveled all over the world, but it was a trip to the eye doctor that took Goodstein down an untraveled path.During a routine eye exam, Goodstein's doctor revealed she had glaucoma. "It was scary," Goodstein said. Goodstein had no idea anything was wrong. She didn't have any symptoms. "I really had no idea what it was until my eye doctor told me my pressure was too high," Goodstein said. Goodstein's eyesight was in jeopardy, which would make day-to-day tasks difficult. "I would have lost my peripheral vision, which means I would have not been able to drive and not been able to see very well," Goodstein said. In addition to the glaucoma, Goodstein developed a cataract, which compromised her vision even more. However, the new development made her a candidate for a new option only one Milwaukee doctor could offer.
Drinks That Will Improve Your Eye Sight
Having keen senses can make anyone feel like a superhero, and eagle-eye vision is particularly useful. We are all told as children to eat our fruits and veggies, and though many of us have rolled our eyes and gone on with our picky eater ways, there was (and is) a lot of merit to that nagging command. Healthy eyes and good vision play a critical role as we grow and age. Pregnant women especially should eat well and make sure they are getting all the vitamins and minerals not only for themselves, but for the new life growing inside. We all know that aging impacts vision, be it through cataracts and astigmatism or just declining vision in general. Eating a diet rich in fresh fruits and vegetables, especially those rich in color (a pretty reliable sign that they’re extra nutritious), can give anyone an edge in not only maintaining great health, but sharpening all the senses. Fruits and vegetables also provide an invaluable source of protein, almost twice as much as that found in animal protein such as dairy or meats. Plant proteins contain amino acids that are easily assimilated and incorporated into the body....
Stem cell secretions may help treat glaucoma
Glaucoma is a group of disorders that can cause serious vision impairment. Although there is no known cure, treatment can delay the disease. Emerging research uncovers a new potential treatment option that uses stem cell secretions.New research suggests that stem cell secretions could help to treat glaucoma and other optic neuropathies.Glaucomadamages the optic nerve and can ultimately cause blindness. In the United States, the disorder affects approximately1.9 percentof people aged 40 and over, with 2.7 million U.S. seniors living with primary glaucoma. There is currently no cure for the disease, as glaucoma-affected vision cannot be restored. However, early treatmentcan delaythe progression of the symptoms and save the vision that remains unaffected. Such treatment options are widely available and include medication and laser surgery. According to a new study,stem cellresearch has also shown promise for treatment. Mesenchymal stem cells (MSC) have been shown to have protective effects on retinal ganglion cells. The loss of these latter cells and their axons is one of the leading causes of degenerative eye diseases such as glaucoma.
World first: Surgical eye robot performs precision-injection in patient with retinal vein occlusion
Surgeons at University Hospitals Leuven have been the first to operate on a patient with retinal vein occlusion using a surgical robot. Operated by an eye surgeon, the robot uses a needle of barely 0.03 millimetre to inject a thrombolytic drug into the retinal vein of the patient. KU Leuven developed the robot and needle specifically for this procedure. The operation was successful and is a real world first: the procedure shows that it is technically possible to safely dissolve a blood clot from the retinal vein with robotic support. A phase 2 trial now has to show what the clinical impact is for patients with retinal vein occlusion, a disorder that can lead to blindness. In case of retinal vein occlusion (RVO) there is a blood clot in one of the retinal veins. This leads to reduced eyesight or even blindness in the eye affected. At the moment, treatment consists of monthly injections in the eye that only reduce the side effects of the thrombosis. Until recently, taking away the blood clot itself was not possible.
Robot Performs World's First Precision Injection on Retinal Vein Occlusion Patient
Surgeons of University Hospitals Leuven have been the first to operate on a patient with retinal vein occlusion using a surgical robot. Operated by an eye surgeon, the robot uses a needle of barely 0.03 millimeter to inject a thrombolytic drug into the retinal vein of the patient. KU Leuven (University of Leuven, Belgium) developed the robot and needle specifically for this procedure. The operation was successful and is a real world first: the procedure shows that it is technically possible to safely dissolve a blood clot from the retinal vein with robotic support. A phase 2 trial now has to show what the clinical impact is for patients with retinal vein occlusion, a disorder that can lead to blindness. In case of retinal vein occlusion (RVO) there is a blood clot in one of the retinal veins. This leads to reduced eyesight or even blindness in the eye affected. At the moment, treatment consists of monthly injections in the eye that only reduce the side effects of the thrombosis. Until recently, taking away the blood clot itself was not possible. Researchers at University Hospitals Leuven and KU Leuven are studying retinal vein cannulation (RVC), a revolutionary treatment that addresses the cause of retinal vein occlusion by removing the blood clot in the retinal vein. RVC is a promising method requiring the eye surgeon to insert an ultrathin needle into the vein and to inject a medicine that can dissolve the blood clot. A real feat, because a retinal vein only has the width of a tenth of a millimeter, about the same width as a human hair. No surgeon is able to manually inject a drug into such a thin vein while holding the needle perfectly still for 10 minutes. The danger of damaging the vein or the retina would be simply too high. This is why researchers from the department of mechanical engineering of KU Leuven developed a robotic device enabling the surgeon to insert the needle into the veins in a very precise and stable way, after which the robot can hold the needle perfectly immobile. In contrast to most surgical robots, there is no need for a joystick to operate the device. The eye surgeon and the robot co-manipulate the instrument. The surgeon guides the needle into the vein while the robot eliminates any vibration of the needle, hereby increasing the level of precision more than tenfold. After locking the robot, the needle and the eye are automatically stabilized. The surgeon can then inject the product into the vein in a controlled way. The researchers also found a way of producing an ultrathin injection needle: the needle point has a width of barely 0.03 millimeter, three times thinner than a human hair. The robot is the result of seven years of research and cooperation between KU Leuven engineers and University Hospitals Leuven ophthalmologists. The current phase 1 trial aims to demonstrate that it is technically feasible to use a robotic device to insert a microneedle into the retinal vein and to inject the product Ocriplasmin to dissolve the blood clot. On the 12th of January 2017 the procedure was performed for the first time in a University Hospitals Leuven patient. The patient is doing well and can now start working on the rehabilitation of the eye. In a subsequent phase 2 trial the physicians will study the clinical effects of the procedure. Prof. dr. Peter Stalmans; eye surgeon at University Hospitals Leuven: "Current treatment for retinal vein occlusion is costing society €32,000 per eye, a high price tag, especially if you know that you are only treating the side effects and that there is little more you can do than avoid decreasing eye sight. The robotic device enables us to treat the cause of the thrombosis in the retina for the first time. I am therefore looking forward to what is next: if we succeed, we will literally be able to make blind people see again." Prof. dr. ir. Dominiek Reynaerts, KU Leuven Department of Mechanical Engineering: "We are hugely proud that our robot enables us to perform eye surgery that was previously impossible to perform safely. This brings us one step closer to commercializing this groundbreaking technology. We look forward to making other revolutionary procedures possible with this robotic device and to improving the quality of existing surgical treatments." Worldwide there are 16.4 million people with a blocked retinal vein caused by thrombosis in the blood vessel. In Belgium, there are about 25,000 patients. - See more at: http://www.mpo-mag.com/contents/view_videos/2017-01-26/robot-performs-worlds-first-precision-injection-on-retinal-vein-occlusion-patient/#sthash.lDkVheQK.dpuf ...
OptimizeRx Integrates with Eye Care Leaders to Deliver Improved Eye Care and Cost Savings on Prescriptions
DURHAM, N.C. and ROCHESTER, Mich., Jan. 24, 2017 (GLOBE NEWSWIRE) -- Eye Care Leaders (ECL), the leading provider of practice performance solutions for ophthalmologists and optometrists, has integrated with OptimizeRx Corp. (OTCQB:OPRX), the leading aggregator of pharmaceutical-sponsored services in electronic health record (EHR) platforms. Through a dynamic platform integration, ECL and OptimizeRx will provide cost saving and patient information services within EHRs that are part of ECL’s portfolio of performance solutions for more than 6,800 ophthalmologists and optometrists. ECL brings together the most trusted names in EHR technology, including Medflow, Integrity EMR, MDoffice, ManagementPlus, IO Practiceware and EyeDoc. ...
Low-cost therapy produces long-lasting improvements for stroke survivors
A new study by researchers at the University of East Anglia (UEA) and the University of Glasgow has found that a low-cost therapy can improve the lives of stroke patients with vision problems. A stroke can affect the way the brain processes the information it receives from the eyes which can cause a number of visual processing problems. The study aimed to test the effectiveness of visuomotor feedback training (VFT) in treating the most common of these, visual neglect, which happens when the brain does not process the information about what is seen on one side of space. Patients with visual neglect may not be aware of the left or right side depending on the side of their stroke. For example, if the stroke affects the right side of the brain then patients will have problems processing the left side. This means they might accidentally ignore people, or even their own body, and may bump into things because they do not realise they are there.
Study On Post-Lasik Quality Of Life
The American Society of Cataract and Refractive Surgery (ASCRS) has announced that it will participate in a post-LASIK quality of life study with the Joint LASIK Study Task Force, which includes the U.S. Food and Drug Administration (FDA), the National Eye Institute (NEI), ASCRS and the American Academy of Ophthalmology. ASCRS also announced that the ASCRS Foundation has committed funds to support this effort. The FDA reaffirms that LASIK is both safe and effective. The Joint LASIK Study Task Force now will examine LASIK'S impact on the quality of patients' daily lives. Simply defined, quality of life refers to a patient's ability to perform the activities of daily living, everything from driving, daily routine, family life, career and sports performance, to personal appearance, after LASIK. While the FDA reports that nearly all patients are satisfied with their procedure, the study will seek to qualify LASIK's benefits and provide greater understanding of the very few patients whose expectations are not met with the procedure, with the goal of identifying ways to enhance patient care.
Which Vitamins are Good for Dry Eyes?
Learn about eye health and what specific vitamins may treat symptoms of dry eyes. What other treatments and possible home remedies are available also?
Improving longevity of functionally integrated stem cells in regenerative vision therapy
Stem cell therapies hold great promise for restoring function in a variety of degenerative conditions, but one of the logistical hurdles is how to ensure the cells survive in the body long enough to work. Researchers from the Buck Institute report one of the first demonstrations of long-term vision restoration in blind mice by transplanting photoreceptors derived from human stem cells and blocking the immune response that causes transplanted cells to be rejected by the recipient. Publishing in the
Paragon CRT® Contact Lenses Approved by China Food & Drug Administration
MESA, Ariz., Jan. 11, 2017 /PRNewswire/ -- Paragon Vision Sciences, a world leader in orthokeratology, today announced China Food and Drug Administration (CFDA) approval and commercial availability of its corneal reshaping/ orthokeratology brand, Paragon CRT® Contact Lenses in China. The contact lenses, a non-surgical treatment option for managing myopia (nearsightedness), the leading cause of vision impairment worldwide1, are now available in 50 countries around the world, including the United States. In China, one out of three people above the age of five suffers from myopia (a vision condition in which people can see close objects clearly, but objects farther away appear blurred) according to the National Visual Health White paper released in June 2016 by the China Health Development Research Center at Peking University.
Mass. Eye and Ear Launches Health Blog Related to Ear, Nose, Throat and Eye Care
Newswise — Boston, Mass. — Massachusetts Eye and Ear has launched a health blog to provide stories and insight from experts in otolaryngology (ear, nose, throat, head and neck care) and ophthalmology (eye care) to those interested in the hospital’s mission and areas of expertise. The online publication, named Focus, covers a range of topics in the form of expert commentary on common conditions, profiles of medical and research trainees, research findings and patient stories. “Mass. Eye and Ear occupies a special niche within the healthcare and medical research community, and we felt that our stories of fighting blindness, deafness, head and neck cancer and other conditions were in need of an online space to be shared,” said Jennifer Street, Vice President of Communications and Planning at Mass. Eye and Ear. “With Focus, our goal is to make our research, clinical care and training programs in ophthalmology and otolaryngology more accessible to our patients, who we want to have the best experience possible in the healthcare environment.”
LASIK and Dry Eyes: What's the Connection?
LASIK is a popular way of correcting vision, but complications can include dry eyes. Learn more about LASIK, dry eyes, and other vision correction options. Laser-Assisted In Situ Keratomileusis, known as LASIK, is the most common type of laser eye surgery. It is used to treat nearsightedness, farsightedness, and astigmatism. According to the United States Food and Drug Administration, the procedure entails a number of unavoidable risks and complications in some patients. The most common complication is dry eyes. What is LASIK? Laser eye surgery is a popular way of correcting vision. The LASIK procedure starts with the surgeon applying eye drops to numb the eye and then propping open the eyelids using an instrument called a lid speculum. The surgeon creates a thin flap in the cornea - the eye's outermost layer - which is temporarily folded away. Using a computer-controlled laser, pulses of light are focused on the eye, and these reshape the cornea. Finally, the LASIK surgeon repositions the corneal flap, and this will begin to heal on its own within hours. People undergoing LASIK usually feel pressure on the eye, an itching sensation, or slight burning, but the procedure is not usually painful.
Eye surgery of the future: Gentle, efficient, out-patient surgery
The eye surgery of the future will be performed on an out-patient basis, will be gentle and efficient. "Our vision for the future is an eye clinic with no beds," says Ursula Schmidt-Erfurth, Head of the Department of Ophthalmology and Optometrics, speaking at a press conference prior to the ART 2016 specialist conference (Advanced Retinal Therapy), taking place in Vienna this coming Saturday. Gentle out-patient treatment means that it is pain-free, non-invasive, does not require anaesthesia and only involves a short stay in a day clinic. "This is efficient for the doctors, the patients, who can go straight home - and for the health system, because it is extremely cost saving," says Schmidt-Erfurth, in summary. For many years now, cataract operations have been done on a day-surgery basis and now the last bastion of complex eye surgery is also about to take this revolutionary step. There is lively debate among the scientific ophthalmology community as to whether an eye hospital still needs patient beds and whether the standard follow-up examinations following major eye procedures are even necessary. Schmidt-Erfurth: "Colleagues in the USA are already performing major retinal procedures in the ophthalmologist's office rather than in hospitals."
Smart cane could transform lives of the blind and visually impaired
An enterprising researcher from The University of Manchester has developed a prototype tool that could help transform the lives of the blind and visually impaired. Vasileios Tsormpatzoudis has upgraded the white cane - which has been used as a mobility tool for centuries - by adding a low-cost embedded computer that functions in a similar way to a car parking sensor. PhD student Vasileios, from the University's School of Electrical and Electronic Engineering, was inspired to develop mySmartCane after witnessing the struggles of his mother who has retinis pigmentosa, a hereditary eye disorder which affects the retina. "mySmartCane allows visual impaired people to sense their environment beyond the physical length of their cane," said Vasileios Tsormpatzoudis, who is researching energy storage and power network integration at The University of Manchester. "The user is alerted to approaching objects using gentle audio, rather than waiting for the cane to physically bump into the object. Navigation is therefore easier and much faster."
New gene-editing technology partially restores vision in blind animals
Salk Institute researchers have discovered a holy grail of gene editing - the ability to, for the first time, insert DNA at a target location into the non-dividing cells that make up the majority of adult organs and tissues. The technique, which the team showed was able to partially restore visual responses in blind rodents, will open new avenues for basic research and a variety of treatments, such as for retinal, heart and neurological diseases. "We are very excited by the technology we discovered because it's something that could not be done before," says Juan Carlos Izpisua Belmonte, a professor in Salk's Gene Expression Laboratory and senior author of the paper published in